Gene Symbol | ARHGEF15 |
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Entrez Gene | 22899 |
Alt Symbol | ARGEF15, E5, Ephexin5, Vsm-RhoGEF |
Species | Human |
Gene Type | protein-coding |
Description | Rho guanine nucleotide exchange factor (GEF) 15 |
Other Description | ephexin-5|rho guanine nucleotide exchange factor 15 |
Swissprots | Q8N449 Q9H8B4 A8K6G1 O94989 |
Accessions | EAW90060 EAW90061 O94989 AB020722 BAA74938 AK023853 AK291626 BAF84315 AK300327 BAG62077 AL601528 BC036749 AAH36749 BQ004849 BQ877184 DA632576 DB279954 XM_011523734 XP_011522036 XM_011523735 XP_011522037 XM_011523736 XP_011522038 XM_011523737 XP_011522039 NM_025014 NP_079290 NM_173728 NP_776089 |
Function | Specific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2. {ECO:0000269|PubMed:12775584}. |
Subcellular Location | Cell projection, dendrite {ECO:0000250}. Note=Expressed exclusively in dendrites of the developing hippocampus. {ECO:0000250}. |
Tissue Specificity | Expressed in the vascular smooth muscle of coronary artery. {ECO:0000269|PubMed:12775584}. |
ARHGEF15 (N-12) - sc-160149 from Santa Cruz Biotechnology
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ARHGEF15 (Q-14) - sc-160150 from Santa Cruz Biotechnology
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Anti-Rho guanine exchange factor 15 antibody - ab127704 from Abcam
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Anti-Rho guanine exchange factor 15 antibody - ab170248 from Abcam
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Anti-Rho guanine exchange factor 15 antibody - ab56080 from Abcam
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Anti-ARHGEF15 Antibody (C-Terminus) - LS-C46939 from LifeSpan Bioscience
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ARHGEF15 Antibody - NBP1-91679 from Novus Biologicals
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ARHGEF15 Antibody - NBP2-15455 from Novus Biologicals
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Anti-ARHGEF15 antibody produced in rabbit - HPA044443 from Sigma-Aldrich
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Anti-ARHGEF15 (782-795) antibody produced in rabbit - SAB1101373 from Sigma-Aldrich
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Anti-ARHGEF15 (311-325) antibody produced in rabbit - SAB1101372 from Sigma-Aldrich
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ARHGEF15 Antibody - abx036826 from Abbexa
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ARHGEF15 antibody - PAB5246 from Acris Antibodies
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ARHGEF15 Antibody - 39932 from Signalway Antibody
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ARHGEF15 Antibody - E306487 from Enogene
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ARHGEF15 , Polyclonal Antibody - MBS859506 from MyBioSource
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ARHGEF15 - MBS270766 from MyBioSource
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ARHGEF15, Polyclonal Antibody - MBS417237 from MyBioSource
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Anti-ARHGEF15 (aa 470-668) polyclonal antibody - DPABH-08514 from Creative Diagnostics
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Anti-ARHGEF15 (aa 464-667) polyclonal antibody - DPABH-23251 from Creative Diagnostics
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Anti-ARHGEF15 Antibody (aa470-668) - LS-C348904 from LifeSpan Bioscience
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ARHGEF15 antibody - orb154827 from Biorbyt
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Anti-endotoxin Therapeutic Antibody (edobacomab) - TAB-741 from Creative Biolabs
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