ARHGEF15

Gene Symbol ARHGEF15
Entrez Gene 22899
Alt Symbol ARGEF15, E5, Ephexin5, Vsm-RhoGEF
Species Human
Gene Type protein-coding
Description Rho guanine nucleotide exchange factor (GEF) 15
Other Description ephexin-5|rho guanine nucleotide exchange factor 15
Swissprots Q8N449 Q9H8B4 A8K6G1 O94989
Accessions EAW90060 EAW90061 O94989 AB020722 BAA74938 AK023853 AK291626 BAF84315 AK300327 BAG62077 AL601528 BC036749 AAH36749 BQ004849 BQ877184 DA632576 DB279954 XM_011523734 XP_011522036 XM_011523735 XP_011522037 XM_011523736 XP_011522038 XM_011523737 XP_011522039 NM_025014 NP_079290 NM_173728 NP_776089
Function Specific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2. {ECO:0000269|PubMed:12775584}.
Subcellular Location Cell projection, dendrite {ECO:0000250}. Note=Expressed exclusively in dendrites of the developing hippocampus. {ECO:0000250}.
Tissue Specificity Expressed in the vascular smooth muscle of coronary artery. {ECO:0000269|PubMed:12775584}.

ARHGEF15 overexpression lysate - LY406569 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

ARHGEF15 293 Cell Lysate - 403963 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

ARHGEF15 Over-expression Lysate Product - GWB-B35DD4 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

ARHGEF15 Overexpression Lysate (Native) - NBL1-07679 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: ARHGEF15 Overexpression Lysate (Adult Normal) [NBL1-07679] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ARHGEF15.

Panoply™ Human ARHGEF15 Knockdown Stable Cell Line - CSC-DC000883 from Creative biogene

Category Cell Line
Species Human
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