Gene Symbol | MAFG |
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Entrez Gene | 4097 |
Alt Symbol | hMAF |
Species | Human |
Gene Type | protein-coding |
Description | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
Other Description | basic leucine zipper transcription factor MafG|transcription factor MafG |
Swissprots | O15525 |
Accessions | EAW89712 EAW89715 O15525 AA775797 AF059195 AAC14427 AK130699 AL520760 BC006143 BC012327 AAH12327 BC103722 BE258646 BE264273 BF976800 BI763651 BM721518 BQ212603 BU195720 DQ591919 DQ890709 ABM81635 DR156847 U84249 AAC51737 Y11514 CAA72284 XM_011523575 XP_011521877 XM_011523576 XP_011521878 XM_011523577 XP_011521879 XM_011523578 XP_011521880 XM_011523579 XP_011521881 NM_002359 NP_002350 NM_032711 NP_116100 |
Function | Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF- E2. Activates globin gene expression when associated with NF-E2. May be involved in signal transduction of extracellular H(+) (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978, ECO:0000269|PubMed:11154691}. |
Tissue Specificity | Highly expressed in skeletal muscle. Also expressed in heart and brain. |
Human MAFG full length protein - ab113589 from Abcam
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MAFG peptide - ab113702 from Abcam
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MAFG Antibody Blocking Peptide - LS-E5320 from LifeSpan Bioscience
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MAFG Antibody Blocking Peptide - LS-E11488 from LifeSpan Bioscience
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MAFG Antibody Blocking Peptide - LS-E11186 from LifeSpan Bioscience
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MAFG Antibody Blocking Peptide - LS-E13693 from LifeSpan Bioscience
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MafG Recombinant Protein - H00004097-P01 from Novus Biologicals
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Recombinant Human MafG Protein - NBP1-72507 from Novus Biologicals
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MAFG-Antibody-N-term-Blocking-Peptide - BP17800a from Abgent, a WuXi AppTec company
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Human MAFG protein - orb168763 from Biorbyt
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MAFG protein (His tag) - 80R-2021 from Fitzgerald
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MAFG (1-162, His-tag) - AR50093PU-N from Acris Antibodies
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MAFG (1-162, His-tag) - AR50093PU-S from Acris Antibodies
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MAFG - H00004097-P01-10 from Acris Antibodies
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MAFG - H00004097-P01-25 from Acris Antibodies
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MAFG, 1-162aa, Human, His tag, E.coli - 01-P1268 from ARP American Research Products
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Recombinant Human MAFG Protein - BP001772-PRO-968 from Syd Labs
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MAFG, 1-162aa, Recombinant Protein - GWB-P0770C from Genway Biotech
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Recombinant Human V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog G (Avian), His-tagged - MAFG-4731H from Creative Biomart
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MAFG 1-162aa - CMB-1101 from Reagent Proteins
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Recombinant Human Transcription factor MafG(MAFG) - CSB-YP013319HU CSB-EP013319HU CSB-BP013319HU CSB-MP013319HU from Cusabio
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MAFG, 1-162aa, Human, His tag, E.coli - ATGP1268 from ATGen
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MAFG (transcript variant 1) - TP321486 from Acris Antibodies
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V-maf Musculoaponeurotic Fibrosarcoma Oncogene G, Recombinant Protein - MBS145242 from MyBioSource
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MAFG Peptide, Human - M34GP09075H from Creative Peptides
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