Gene Symbol | MAFG |
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Entrez Gene | 4097 |
Alt Symbol | hMAF |
Species | Human |
Gene Type | protein-coding |
Description | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
Other Description | basic leucine zipper transcription factor MafG|transcription factor MafG |
Swissprots | O15525 |
Accessions | EAW89712 EAW89715 O15525 AA775797 AF059195 AAC14427 AK130699 AL520760 BC006143 BC012327 AAH12327 BC103722 BE258646 BE264273 BF976800 BI763651 BM721518 BQ212603 BU195720 DQ591919 DQ890709 ABM81635 DR156847 U84249 AAC51737 Y11514 CAA72284 XM_011523575 XP_011521877 XM_011523576 XP_011521878 XM_011523577 XP_011521879 XM_011523578 XP_011521880 XM_011523579 XP_011521881 NM_002359 NP_002350 NM_032711 NP_116100 |
Function | Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF- E2. Activates globin gene expression when associated with NF-E2. May be involved in signal transduction of extracellular H(+) (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978, ECO:0000269|PubMed:11154691}. |
Tissue Specificity | Highly expressed in skeletal muscle. Also expressed in heart and brain. |
MafG (Y-25) - sc-133770 from Santa Cruz Biotechnology
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MafF/G/K (C-18) - sc-16278 from Santa Cruz Biotechnology
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MafF/G/K (H-100) - sc-22831 from Santa Cruz Biotechnology
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Anti-MAFG antibody - ab154318 from Abcam
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Anti-MAFG Antibody (N-Terminus) - LS-C169504 from LifeSpan Bioscience
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Anti-MAFG Antibody (aa1-30) - LS-C158092 from LifeSpan Bioscience
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Anti-MAFG Antibody - LS-C37278 from LifeSpan Bioscience
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Anti-MAFG Antibody (aa1-30, AP) - LS-C262424 from LifeSpan Bioscience
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Anti-MAFG Antibody (aa1-30, APC) - LS-C262425 from LifeSpan Bioscience
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Anti-MAFG Antibody (aa1-30, Biotin) - LS-C262426 from LifeSpan Bioscience
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Anti-MAFG Antibody (aa1-30, FITC) - LS-C262427 from LifeSpan Bioscience
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Anti-MAFG Antibody (N-Terminus) - LS-C30449 from LifeSpan Bioscience
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Anti-MAFG Antibody (aa1-30, PE) - LS-C262430 from LifeSpan Bioscience
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Anti-MAFG Antibody (aa1-30, Azide-free, HRP) - LS-C262428 from LifeSpan Bioscience
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Anti-MAFG Antibody - LS-C308850 from LifeSpan Bioscience
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Anti-MAFG Antibody (aa71-120) - LS-C101405 from LifeSpan Bioscience
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Anti-MAFG Antibody (aa1-30) - LS-C322796 from LifeSpan Bioscience
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MafG Antibody - NBP2-15019 from Novus Biologicals
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MafG Antibody (370412) - MAB3924 from Novus Biologicals
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MafG Antibody - H00004097-B01P from Novus Biologicals
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MafG Antibody - H00004097-B01 from Novus Biologicals
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Anti-MAFG antibody produced in mouse - SAB1406099 from Sigma-Aldrich
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Anti-MAFG antibody produced in rabbit - AV38143 from Sigma-Aldrich
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Anti-MAFG antibody produced in rabbit - SAB2702084 from Sigma-Aldrich
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Anti-MAFG antibody produced in rabbit - SAB2101416 from Sigma-Aldrich
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