SPINK5

Gene Symbol	SPINK5
Entrez Gene	11005
Alt Symbol	LEKTI, LETKI, NETS, NS, VAKTI
Species	Human
Gene Type	protein-coding
Description	serine peptidase inhibitor, Kazal type 5
Other Description	lympho-epithelial Kazal-type-related inhibitor|lymphoepithelial Kazal-type-related inhibitor|serine protease inhibitor Kazal-type 5|serine protease inhibitor, Kazal type 5
Swissprots	A8MYE8 Q3LX97 Q9NQ38 D6REN5 Q96PP3 Q96PP2 B7WPB7 Q3LX95 O75770 Q3LX96
Accessions	AAK97139 AAK97140 CAB96877 EAW61815 Q9NQ38 AF086524 AF147363 AI341060 AJ228139 CAB40839 AK025197 AK299455 BAG61426 AK301660 BAG63135 AK307588 AK307648 AK309753 BC141545 AAI41546 BI256857 BX648792 DQ149927 ABA06534 DQ149928 ABA06535 DQ149929 ABA06536 DR421881 XM_011537550 XP_011535852 XM_011537551 XP_011535853 NM_001127698 NP_001121170 NM_001127699 NP_001121171 NM_006846 NP_006837
Function	Serine protease inhibitor, probably important for the anti-inflammatory and/or antimicrobial protection of mucous epithelia. Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense- activating and desquamation-involved proteases. Inhibits KLK5, it's major target, in a pH-dependent manner. Inhibits KLK7, KLK14 CASP14, and trypsin. {ECO:0000269|PubMed:10419450, ECO:0000269|PubMed:17596512, ECO:0000269|PubMed:20533828}.
Subcellular Location	Secreted.
Tissue Specificity	Highly expressed in the thymus and stratum corneum. Also found in the oral mucosa, parathyroid gland, Bartholin's glands, tonsils, and vaginal epithelium. Very low levels are detected in lung, kidney, and prostate. {ECO:0000269|PubMed:10419450}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SPINK5 / LEKTI ELISA Kit (Sandwich ELISA) - LS-F7754 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.312 ng/ml Range 0.312-20 ng/ml

Mouse SPINK5 / LEKTI ELISA Kit (Sandwich ELISA) - LS-F9406 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 29 pg/ml Range 0.312-20 ng/ml

Serine Peptidase Inhibitor Kazal Type 5 (SPINK5), Human, ELISA Kit - SEH145Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.116ng/mL Range 0.312-20ng/mL

Serine protease inhibitor Kazal-type 5 (SPINK5), Human, ELISA Kit - CSB-EL022578HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 15.6pg/ml Range 62.5 pg/ml-4000 pg/ml

Serine Peptidase Inhibitor Kazal Type 5 (SPINK5), ELISA Kit - MBS2019519 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.113ng/mL. Range 0.313-20ng/mL

Serine Peptidase Inhibitor Kazal Type 5 (SPINK5), ELISA Kit - MBS2023641 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 29pg/mL. Range 78.13-5000pg/mL

serine peptidase inhibitor, Kazal type 5, ELISA Kit - MBS942561 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <15.6 pg/ml Range 62.5 pg/ml-4000 pg/ml

skin reactive factor / inflammatory factor (SRF / IF), ELISA Kit - MBS267789 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

skin reactive factor / inflammatory factor (SRF / IF), ELISA Kit - MBS265766 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

skin reactive factor / inflammatory factor (SRF / IF), ELISA Kit - MBS264766 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

skin reactive factor / inflammatory factor (SRF / IF), ELISA Kit - MBS260189 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

skin reactive factor / inflammatory factor (SRF / IF), ELISA Kit - MBS262752 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

skin reactive factor / inflammatory factor (SRF / IF), ELISA Kit - MBS264052 from MyBioSource Category ELISA Kit Prices $275.00, $420.00, $1,615.00, $2,880.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

skin reactive factor / inflammatory factor (SRF / IF), ELISA Kit - MBS2600863 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

skin reactive factor / inflammatory factor (SRF / IF), ELISA Kit - MBS269818 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) - SEH145Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.113ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) - SEH145Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 29pg/mL. Range 78.13-5000pg/mL The standard curve concentrations used for the ELISA’s were 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312.5pg/mL, 156.25pg/mL, 78.13pg/mL

Human Serine protease inhibitor Kazal-type 5(SPINK5) ELISA kit - CSB-EL022578HU from Cusabio Category ELISA Kit Sensitivity 15.6 pg/ml Range 62.5 pg/ml-4000 pg/ml

ELISA Kit for Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) - SEH145Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.113ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human SPINK5 ELISA Kit - abx153154 from Abbexa Category ELISA Kit Sensitivity 0.116 ng/ml Range 0.313 ng/ml - 20 ng/ml

Serine Peptidase Inhibitor Kazal Type 5 (SPINK5), Human, ELISA Kit - DL-SPINK5-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

Human SPINK5 ELISA Kit - abx572637 from Abbexa Category ELISA Kit Sensitivity 0.116 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human Serine protease inhibitor Kazal-type 5 (SPINK5) ELISA Kit - EKC35505 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 15.6 pg/ml Range 62.5 pg/ml-4000 pg/ml

Custom Human LEKTI/SPINK5 ELISA - ELH-LEKTI-1 from RayBiotech Category ELISA Kit Prices $627.00, $1,128.60, $2,508.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Custom Human SPINK5 ELISA Kit - orb384640 from Biorbyt Category ELISA Kit Prices $1,411.00, $2,448.00, $5,321.00 Sizes 96 assays, 192 assays, 480 assays

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