AGL
| Gene Symbol | AGL |
|---|---|
| Entrez Gene | 178 |
| Alt Symbol | GDE |
| Species | Human |
| Gene Type | protein-coding |
| Description | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
| Other Description | amylo-1, 6-glucosidase, 4-alpha-glucanotransferase|glycogen debrancher|glycogen debranching enzyme |
| Swissprots | A6NEK2 P35573 P78354 D3DT51 Q6AZ90 P78544 A6NCX7 Q59H92 Q9UF08 |
| Accessions | BAA88405 EAW72980 EAW72981 EAW72982 EAW72983 EAW72984 EAW72985 EAW72986 EAW72987 P35573 AB208867 BAD92104 AB621804 BAK64140 AK130308 BC020705 BC057220 BC078663 AAH78663 C00487 M85168 AAB41040 U84007 AAB48466 U84008 AAB48467 U84009 AAB48468 U84010 AAB48469 U84011 AAB48470 XM_005270557 XP_005270614 NM_000028 NP_000019 NM_000642 NP_000633 NM_000643 NP_000634 NM_000644 NP_000635 NM_000645 NP_000636 NM_000646 NP_000637 |
| Function | Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4- alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6- glucosidase in glycogen degradation. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17908927}. Note=Under glycogenolytic conditions localizes to the nucleus. |
| Tissue Specificity | Liver, kidney and lymphoblastoid cells express predominantly isoform 1; whereas muscle and heart express not only isoform 1, but also muscle-specific isoform mRNAs (isoforms 2, 3 and 4). Isoforms 5 and 6 are present in both liver and muscle. |
| Top Pathways | Starch and sucrose metabolism |
AGL (C-18) - sc-130115 from Santa Cruz Biotechnology
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AGL (N-16) - sc-161316 from Santa Cruz Biotechnology
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AGL (S-15) - sc-161317 from Santa Cruz Biotechnology
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Anti-AGL antibody - ab198713 from Abcam
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Anti-AGL antibody - ab72770 from Abcam
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Anti-AGL antibody [EPR8880] - ab133720 from Abcam
![All lanes : Anti-AGL antibody [EPR8880] (ab133720) at 1/1000 dilutionLane 1 : Human fetal muscle lysateLane 2 : Mouse muscle lysateLane 3 : Human fetal heart lysateLane 4 : K562 cell lysateLane 5 : 293T cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution](http://www.bioprodhub.com/system/product_images/ab_products/2/sub_1/3575_AGL-Primary-antibodies-ab133720-1.jpg)
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Anti-AGL antibody - C-terminal - ab71423 from Abcam
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Anti-AGL Antibody (aa1487-1516, AP) - LS-C212630 from LifeSpan Bioscience
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Anti-AGL Antibody (aa1487-1516, Biotin) - LS-C212631 from LifeSpan Bioscience
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Anti-AGL Antibody (aa1487-1516, FITC) - LS-C212634 from LifeSpan Bioscience
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Anti-AGL Antibody (aa1487-1516, Azide-free, HRP) - LS-C212635 from LifeSpan Bioscience
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Anti-AGL Antibody (aa1487-1516, APC) - LS-C212632 from LifeSpan Bioscience
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Anti-AGL Antibody (N-Terminus, APC) - LS-C212637 from LifeSpan Bioscience
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Anti-AGL Antibody (aa1487-1516, PE) - LS-C212636 from LifeSpan Bioscience
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Anti-AGL Antibody (N-Terminus, AP) - LS-C212638 from LifeSpan Bioscience
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Anti-AGL Antibody (N-Terminus, Biotin) - LS-C212639 from LifeSpan Bioscience
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Anti-AGL Antibody (N-Terminus, FITC) - LS-C212640 from LifeSpan Bioscience
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Anti-AGL Antibody (N-Terminus, PE) - LS-C212643 from LifeSpan Bioscience
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Anti-AGL Antibody - LS-C306133 from LifeSpan Bioscience
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Anti-AGL Antibody (N-Terminus, Azide-free, HRP) - LS-C212641 from LifeSpan Bioscience
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Anti-AGL Antibody (N-Terminus) - LS-C319383 from LifeSpan Bioscience
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Anti-AGL Antibody (aa1487-1516) - LS-C329205 from LifeSpan Bioscience
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Anti-AGL Antibody (aa1167-1374) - LS-C311511 from LifeSpan Bioscience
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Anti-AGL Antibody (aa1479-1510) - LS-C99696 from LifeSpan Bioscience
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Anti-AGL Antibody (Internal, clone EPR8880) - LS-C154645 from LifeSpan Bioscience
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