Gene Symbol | AGL |
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Entrez Gene | 178 |
Alt Symbol | GDE |
Species | Human |
Gene Type | protein-coding |
Description | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
Other Description | amylo-1, 6-glucosidase, 4-alpha-glucanotransferase|glycogen debrancher|glycogen debranching enzyme |
Swissprots | A6NEK2 P35573 P78354 D3DT51 Q6AZ90 P78544 A6NCX7 Q59H92 Q9UF08 |
Accessions | BAA88405 EAW72980 EAW72981 EAW72982 EAW72983 EAW72984 EAW72985 EAW72986 EAW72987 P35573 AB208867 BAD92104 AB621804 BAK64140 AK130308 BC020705 BC057220 BC078663 AAH78663 C00487 M85168 AAB41040 U84007 AAB48466 U84008 AAB48467 U84009 AAB48468 U84010 AAB48469 U84011 AAB48470 XM_005270557 XP_005270614 NM_000028 NP_000019 NM_000642 NP_000633 NM_000643 NP_000634 NM_000644 NP_000635 NM_000645 NP_000636 NM_000646 NP_000637 |
Function | Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4- alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6- glucosidase in glycogen degradation. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17908927}. Note=Under glycogenolytic conditions localizes to the nucleus. |
Tissue Specificity | Liver, kidney and lymphoblastoid cells express predominantly isoform 1; whereas muscle and heart express not only isoform 1, but also muscle-specific isoform mRNAs (isoforms 2, 3 and 4). Isoforms 5 and 6 are present in both liver and muscle. |
Top Pathways | Starch and sucrose metabolism |
AGL Antibody Blocking Peptide - LS-E6948 from LifeSpan Bioscience
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AGL Peptide - P1075 from Novus Biologicals
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AGL-Antibody-C-term-Blocking-Peptide - BP2402b from Abgent, a WuXi AppTec company
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AGL fusion protein - ag9962 from Proteintech Group
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AGL fusion protein - Ag9944 from Proteintech Group
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Recombinant Human Glycogen debranching enzyme(AGL) ,partial - CSB-YP001446HU CSB-EP001446HU CSB-BP001446HU CSB-MP001446HU from Cusabio
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AGL / GDE (transcript variant 1) - TP310005 from Acris Antibodies
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AGL / GDE (transcript variant 3) - TP315018 from Acris Antibodies
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AGL / GDE (transcript variant 4) - TP315495 from Acris Antibodies
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AGL Protein - NBP1-89440PEP from Novus Biologicals
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AGL-Antibody-N-term-Blocking-Peptide - BP2402c from Abgent, a WuXi AppTec company
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AGL-Antibody-Center-Blocking-Peptide - BP2402a from Abgent, a WuXi AppTec company
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AGL Peptide, Human - M34GP00375H from Creative Peptides
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Glycogen debranching enzyme (980-990) - ta-084 from Creative Peptides
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Recombinant Glycogen Debranching Enzyme (AGL) - RPU50662 from Biomatik
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AGL Recombinant Protein Antigen - NBP2-55436PEP from Novus Biologicals
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Glycogen Debranching Enzyme, Recombinant Protein - MBS2034545 from MyBioSource
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Glycogen debranching enzyme (AGL), partial, Recombinant Protein - MBS948896 from MyBioSource
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