AGL

Gene Symbol	AGL
Entrez Gene	178
Alt Symbol	GDE
Species	Human
Gene Type	protein-coding
Description	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
Other Description	amylo-1, 6-glucosidase, 4-alpha-glucanotransferase|glycogen debrancher|glycogen debranching enzyme
Swissprots	A6NEK2 P35573 P78354 D3DT51 Q6AZ90 P78544 A6NCX7 Q59H92 Q9UF08
Accessions	BAA88405 EAW72980 EAW72981 EAW72982 EAW72983 EAW72984 EAW72985 EAW72986 EAW72987 P35573 AB208867 BAD92104 AB621804 BAK64140 AK130308 BC020705 BC057220 BC078663 AAH78663 C00487 M85168 AAB41040 U84007 AAB48466 U84008 AAB48467 U84009 AAB48468 U84010 AAB48469 U84011 AAB48470 XM_005270557 XP_005270614 NM_000028 NP_000019 NM_000642 NP_000633 NM_000643 NP_000634 NM_000644 NP_000635 NM_000645 NP_000636 NM_000646 NP_000637
Function	Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4- alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6- glucosidase in glycogen degradation.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:17908927}. Note=Under glycogenolytic conditions localizes to the nucleus.
Tissue Specificity	Liver, kidney and lymphoblastoid cells express predominantly isoform 1; whereas muscle and heart express not only isoform 1, but also muscle-specific isoform mRNAs (isoforms 2, 3 and 4). Isoforms 5 and 6 are present in both liver and muscle.
Top Pathways	Starch and sucrose metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

AGL CRISPR/Cas9 KO Plasmid (h) - sc-408709 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

AGL HDR Plasmid (h) - sc-408709-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

AGL Double Nickase Plasmid (h) - sc-408709-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

AGL Double Nickase Plasmid (h2) - sc-408709-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

AGL CRISPR Activation Plasmid (h) - sc-408709-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

AGL CRISPR Activation Plasmid (h2) - sc-408709-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

AGL Lentiviral Activation Particles (h) - sc-408709-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

AGL Lentiviral Activation Particles (h2) - sc-408709-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

AGL siRNA (h) - sc-88368 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

AGL shRNA Plasmid (h) - sc-88368-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

AGL shRNA (h) Lentiviral Particles - sc-88368-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU077141 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2946 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2946 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11532 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr11532

AGL siRNA (Human) - CRH0126 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

AGL - MBS827697 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human AGL (NM_000028.2) - SHH233290 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human AGL(NM_000645.2) - SHG045361 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human AGL(NM_000646.2) - SHG045415 from Creative biogene Category siRNA Species Reactivities Human

Human AGL siRNA - orb260628 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

AGL shRNA Plasmid (Human) - CHH0126 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

AGL miRNA 3'UTR clone - MiUTR1H-00235 from Creative biogene Species Reactivities Human

AGL miRNA 3'UTR clone - MiUTR1H-00236 from Creative biogene Species Reactivities Human

AGL miRNA 3'UTR clone - MiUTR1H-00237 from Creative biogene Species Reactivities Human

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