Gene Symbol | AGL |
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Entrez Gene | 178 |
Alt Symbol | GDE |
Species | Human |
Gene Type | protein-coding |
Description | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
Other Description | amylo-1, 6-glucosidase, 4-alpha-glucanotransferase|glycogen debrancher|glycogen debranching enzyme |
Swissprots | A6NEK2 P35573 P78354 D3DT51 Q6AZ90 P78544 A6NCX7 Q59H92 Q9UF08 |
Accessions | BAA88405 EAW72980 EAW72981 EAW72982 EAW72983 EAW72984 EAW72985 EAW72986 EAW72987 P35573 AB208867 BAD92104 AB621804 BAK64140 AK130308 BC020705 BC057220 BC078663 AAH78663 C00487 M85168 AAB41040 U84007 AAB48466 U84008 AAB48467 U84009 AAB48468 U84010 AAB48469 U84011 AAB48470 XM_005270557 XP_005270614 NM_000028 NP_000019 NM_000642 NP_000633 NM_000643 NP_000634 NM_000644 NP_000635 NM_000645 NP_000636 NM_000646 NP_000637 |
Function | Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4- alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6- glucosidase in glycogen degradation. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17908927}. Note=Under glycogenolytic conditions localizes to the nucleus. |
Tissue Specificity | Liver, kidney and lymphoblastoid cells express predominantly isoform 1; whereas muscle and heart express not only isoform 1, but also muscle-specific isoform mRNAs (isoforms 2, 3 and 4). Isoforms 5 and 6 are present in both liver and muscle. |
Top Pathways | Starch and sucrose metabolism |
AGL 293T Cell Transient Overexpression Lysate(Denatured) - H00000178-T01 from Acris Antibodies
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AGL overexpression lysate - LY424591 from Acris Antibodies
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AGL overexpression lysate - LY424592 from Acris Antibodies
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AGL overexpression lysate - LY424593 from Acris Antibodies
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AGL overexpression lysate - LY424972 from Acris Antibodies
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AGL overexpression lysate - LY425004 from Acris Antibodies
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AGL overexpression lysate - LY425005 from Acris Antibodies
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AGL overexpression lysate - LY425006 from Acris Antibodies
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AGL 293 Cell Lysate - 410167 from ABBIOTEC
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AGL 293 Cell Lysate - 410348 from ABBIOTEC
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AGL Overexpression Lysate (Denatured) - H00000178-T01 from Novus Biologicals
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AGL Overexpression Lysate (Native) - NBL1-07380 from Novus Biologicals
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AGL Overexpression Lysate (Native) - NBP2-09076 from Novus Biologicals
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AGL Overexpression Lysate (Native) - NBP2-09075 from Novus Biologicals
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AGL Overexpression Lysate (Native) - NBP2-09074 from Novus Biologicals
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AGL Overexpression Lysate (Native) - NBP2-09003 from Novus Biologicals
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AGL Overexpression Lysate (Native) - NBP2-09002 from Novus Biologicals
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AGL Overexpression Lysate (Native) - NBP2-09001 from Novus Biologicals
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AGL Over-expression Lysate Product - GWB-ECDF6F from Genway Biotech
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AGL Over-expression Lysate Product - GWB-CE3B9D from Genway Biotech
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Panoply™ Human AGL Knockdown Stable Cell Line - CSC-DC000375 from Creative biogene
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