NEK11

Gene Symbol NEK11
Entrez Gene 79858
Alt Symbol -
Species Human
Gene Type protein-coding
Description NIMA-related kinase 11
Other Description NIMA (never in mitosis gene a)- related kinase 11|serine/threonine-protein kinase Nek11
Swissprots Q9H5F4 A6NHD7 Q8TBY1 Q8NG66 Q8NG65 Q5JPC0
Accessions EAW79212 EAW79213 Q8NG66 AB071996 BAC06350 AB071997 BAC06351 AK027148 BAB15672 AK123021 AK293261 BAG56793 AK297300 BAG59768 AK316352 BAH14723 AL833472 CAI46114 BC009414 BC026195 BC028587 AAH28587 BU674219 BX328072 XM_005247783 XP_005247840 XM_005247785 XP_005247842 XM_006713749 XP_006713812 XM_011513165 XP_011511467 XM_011513166 XP_011511468 XM_011513167 XP_011511469 XM_011513168 XP_011511470 XM_011513169 XP_011511471 XM_011513170 XP_011511472 XM_011513171 XP_011511473 XM_011513172 XP_011511474 XM_011513173 XP_011511475 XM_011513174 XP_011511476 XM_011513175 XP_011511477 XM_011513176 XP_011511478 XM_011513177 XP_011511479 XM_011513178 XP_011511480 XM_011513179 XP_011511481 XM_011513180 XP_011511482 XM_011513181 XP_011511483 XM_011513182 XP_011511484 XR_924179 NM_001146003 NP_001139475 NM_024800 NP_079076 NM_145910 NP_665917
Function Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation. {ECO:0000269|PubMed:12154088, ECO:0000269|PubMed:19734889, ECO:0000269|PubMed:20090422}.
Subcellular Location Nucleus. Nucleus, nucleolus. Note=Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase. Accumulates in the nucleolus in G1/S- arrested cells.
Tissue Specificity Poorly expressed in cerebellum, trachea, lung, appendix, and uterus. {ECO:0000269|PubMed:12154088}.

NEK11-Over-expression-Lysate - LY11532a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag NEK11 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NEK11 gene

NEK11 293T Cell Transient Overexpression Lysate(Denatured) - H00079858-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

NEK11 293 Cell Lysate - 405568 from ABBIOTEC

Category Cell Lysate
Prices $672.00
Sizes 100 µg

NEK11 Overexpression Lysate (Native) - NBP2-06284 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: NEK11 Overexpression Lysate (Adult Normal) [NBP2-06284] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NEK11.

NEK11 Over-expression Lysate Product - GWB-123FB8 from Genway Biotech

Category Cell Lysate
Prices $756.00
Sizes 100 µg
Species Human

NEK11 Overexpression Lysate (Denatured) - H00079858-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

NEK11 Overexpression Lysate (Denatured) - H00079858-T02 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

Panoply™ Human NEK11 Knockdown Stable Cell Line - CSC-DC010288 from Creative biogene

Category Cell Line
Species Human
Search more