NEK11

Gene Symbol NEK11
Entrez Gene 79858
Alt Symbol -
Species Human
Gene Type protein-coding
Description NIMA-related kinase 11
Other Description NIMA (never in mitosis gene a)- related kinase 11|serine/threonine-protein kinase Nek11
Swissprots Q9H5F4 A6NHD7 Q8TBY1 Q8NG66 Q8NG65 Q5JPC0
Accessions EAW79212 EAW79213 Q8NG66 AB071996 BAC06350 AB071997 BAC06351 AK027148 BAB15672 AK123021 AK293261 BAG56793 AK297300 BAG59768 AK316352 BAH14723 AL833472 CAI46114 BC009414 BC026195 BC028587 AAH28587 BU674219 BX328072 XM_005247783 XP_005247840 XM_005247785 XP_005247842 XM_006713749 XP_006713812 XM_011513165 XP_011511467 XM_011513166 XP_011511468 XM_011513167 XP_011511469 XM_011513168 XP_011511470 XM_011513169 XP_011511471 XM_011513170 XP_011511472 XM_011513171 XP_011511473 XM_011513172 XP_011511474 XM_011513173 XP_011511475 XM_011513174 XP_011511476 XM_011513175 XP_011511477 XM_011513176 XP_011511478 XM_011513177 XP_011511479 XM_011513178 XP_011511480 XM_011513179 XP_011511481 XM_011513180 XP_011511482 XM_011513181 XP_011511483 XM_011513182 XP_011511484 XR_924179 NM_001146003 NP_001139475 NM_024800 NP_079076 NM_145910 NP_665917
Function Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation. {ECO:0000269|PubMed:12154088, ECO:0000269|PubMed:19734889, ECO:0000269|PubMed:20090422}.
Subcellular Location Nucleus. Nucleus, nucleolus. Note=Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase. Accumulates in the nucleolus in G1/S- arrested cells.
Tissue Specificity Poorly expressed in cerebellum, trachea, lung, appendix, and uterus. {ECO:0000269|PubMed:12154088}.

Nek11 CRISPR/Cas9 KO Plasmid (h) - sc-404923 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek11 HDR Plasmid (h) - sc-404923-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek11 Double Nickase Plasmid (h) - sc-404923-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek11 Double Nickase Plasmid (h2) - sc-404923-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek11 CRISPR Activation Plasmid (h) - sc-404923-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek11 CRISPR Activation Plasmid (h2) - sc-404923-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek11 Lentiviral Activation Particles (h) - sc-404923-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek11 Lentiviral Activation Particles (h2) - sc-404923-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek11 siRNA (h) - sc-78268 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nek11 shRNA Plasmid (h) - sc-78268-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nek11 shRNA (h) Lentiviral Particles - sc-78268-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NEK11 RNAi - H00079858-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU073631 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® siRNA - SIHK1390 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1391 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1392 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN15199 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15199 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06306 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06306

NEK11 siRNA (Human) - CRJ2618 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NEK11 RNAi - H00079858-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human NEK11 (NM_145910.3) - SHH351216 from Creative biogene

Category siRNA
Species Reactivities Human

Human NEK11 siRNA - orb273119 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NEK11 shRNA Plasmid (Human) - CHJ2618 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NEK11 miRNA 3'UTR clone - MiUTR3H-10802 from Creative biogene

Species Reactivities Human
Search more