Gene Symbol | ATP10D |
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Entrez Gene | 57205 |
Alt Symbol | ATPVD |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, class V, type 10D |
Other Description | P4-ATPase flippase complex alpha subunit ATP10D|probable phospholipid-transporting ATPase VD|type IV aminophospholipid transporting ATPase |
Swissprots | D6REN2 Q8NC70 Q96SR3 A2RRC8 Q9P241 |
Accessions | EAW93036 EAW93037 Q9P241 AB040920 BAA96011 AJ441078 CAD29577 AK027598 BAB55221 AK074930 BAC11299 BC057839 AAH57839 BC131535 AAI31536 XM_005248119 XP_005248176 XM_005248120 XP_005248177 XM_011513722 XP_011512024 XM_011513723 XP_011512025 XR_925154 NM_020453 NP_065186 |
Function | Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). {ECO:0000305}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:21914794}; Multi-pass membrane protein {ECO:0000269|PubMed:21914794}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:21914794}. Note=Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not that of TMEM30B. |
Tissue Specificity | Expressed in placenta and, to a lesser extent, in kidney. {ECO:0000269|PubMed:12532265}. |
ATP10D (G-15) - sc-161368 from Santa Cruz Biotechnology
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ATP10D (H-112) - sc-134726 from Santa Cruz Biotechnology
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Anti-ATP10D antibody - ab176999 from Abcam
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Anti-ATP10D antibody - ab151102 from Abcam
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Anti-ATP10D antibody - ab81174 from Abcam
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Anti-ATP10D Antibody (aa886-935) - LS-C135228 from LifeSpan Bioscience
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Anti-ATP10D Antibody (aa1154-1203) IHC-plus™ - LS-B8191 from LifeSpan Bioscience
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ATP10D Antibody - NBP1-59982 from Novus Biologicals
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ATP10D Antibody - NBP2-14327 from Novus Biologicals
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Anti-ATP10D antibody produced in rabbit - SAB2100178 from Sigma-Aldrich
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ATP10D antibody - C-terminal region (ARP49516_P050) - ARP49516_P050 from Aviva Systems Biology
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ATP10D antibody, C-term - GTX46053 from GeneTex
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ATP10D antibody - 70R-6896 from Fitzgerald
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Atp10d antibody - 70R-8816 from Fitzgerald
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ATP10D Antibody - abx036972 from Abbexa
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ATP10D Antibody - 26-413 from ProSci
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ATP10D Antibody - E306969 from Enogene
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ATP10D Antibody - GWB-MR537F from Genway Biotech
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Anti-ATP10D (aa 1324-1421) polyclonal antibody - DPABH-03258 from Creative Diagnostics
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Anti-ATP10D (aa 146-321) polyclonal antibody - DPABH-12243 from Creative Diagnostics
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Atp10d-antibody-middle-region-AI13040 - AI13040 from Abgent, a WuXi AppTec company
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ATP10D, Polyclonal Antibody - MBS5300298 from MyBioSource
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Atp10d, Polyclonal Antibody - MBS5303181 from MyBioSource
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Anti-ATP10D antibody produced in rabbit - HPA050808 from Sigma-Aldrich
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ATP10D antibody - TA338420 from Acris Antibodies
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