Dio3

Gene Symbol	Dio3
Entrez Gene	29475
Alt Symbol	5DIII, DIOIII
Species	Rat
Gene Type	protein-coding
Description	deiodinase, iodothyronine, type III
Other Description	deiodinase, iodothyronine, type 3|type 3 DI|type III iodothyronine deiodinase|type-III 5'-deiodinase
Swissprots	P49897
Accessions	EDL97515 P49897 BM414881 U24282 AAC52241 NM_017210 NP_058906
Function	Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.
Subcellular Location	Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Endosome membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity	Neonatal skin, placenta, skeletal muscle and cerebral cortex. {ECO:0000269|PubMed:7622463}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Rat DIO3 ELISA Kit (Sandwich ELISA) - LS-F8100 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.117 ng/ml Range 0.313-20 ng/ml

Deiodinase, Iodothyronine, Type III (DIO3), Rat, ELISA Kit - SEF989Ra from ARP American Research Products Category ELISA Kit Prices $780.00 Sizes 96 t Sensitivity 0.117ng/mL Range 0.312-20ng/mL

Type III iodothyronine deiodinase, Dio3, Rat, ELISA Kit - E12263r from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t Range 0.156-10 ng/mL

Deiodinase, Iodothyronine, Type III, ELISA Kit - MBS049235 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Deiodinase, Iodothyronine, Type III (DIO3) - SEF989Ra from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.117ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Rat Deiodinase, Iodothyronine, Type III (DIO3) ELISA Kit - EKU03678 from Biomatik Category ELISA Kit Prices $798.00, $3,511.00, $6,384.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.117 ng/mL Range 0.312-20 ng/mL

Rat DIO3 ELISA Kit - abx155442 from Abbexa Category ELISA Kit Sensitivity 0.117 ng/ml Range 0.313 ng/ml - 20 ng/ml

Rat Type III iodothyronine deiodinase ELISA Kit - abx256453 from Abbexa Category ELISA Kit Range 0.156 ng/ml - 10 ng/ml

Rat DIO3 ELISA Kit (Sandwich ELISA) - LS-F13278 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.313-20 ng/ml

Deiodinase, Iodothyronine, Type III (DIO3), Rat, ELISA Kit - DL-DIO3-Ra from ARP American Research Products Category ELISA Kit Prices $715.00 Sizes 96 t Range 0.312-20 ng/mL

Rat DIO3 ELISA Kit - abx572757 from Abbexa Category ELISA Kit Sensitivity 0.117 ng/ml Range 0.313 ng/ml - 20 ng/ml

Rat Type III iodothyronine deiodinase ELISA Kit - EKE55298 from Biomatik Category ELISA Kit Prices $809.60, $3,440.80, $6,476.80 Sizes 96 t, 5x96t, 10x96t Range 0.156-10 ng/mL

Dio3 - EKR0952 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156-10ng/ml

DIO3 ELISA Kit (Rat) : 96 Wells (OKEH02220) - OKEH02220 from Aviva Systems Biology Category ELISA Kit Prices $480.00 Sizes 96 wells Sensitivity < 0.098 ng/mL Range 0.156 - 10 ng/mL

Dio3 - EKR952 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156-10ng/ml

Rat Dio3 ELISA Kit - E086848 from Biobool Category ELISA Kit

Rat Type III iodothyronine deiodinase ELISA Kit - EK3012 from Signalway Antibody Category ELISA Kit Prices $739.00 Sizes 1x96t Range 0.156-10 ng/mL

Deiodinase, Iodothyronine, Type III (DIO3), ELISA Kit - MBS452080 from MyBioSource Category ELISA Kit Prices $440.00, $585.00, $2,595.00, $5,040.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.117ng/mL Range 0.312-20ng/mL

Type III iodothyronine deiodinase, ELISA Kit - MBS9426847 from MyBioSource Category ELISA Kit Prices $670.00 Sizes 96 tests Range 0.156-10 ng/mL

Type III iodothyronine deiodinase, ELISA Kit - MBS2887623 from MyBioSource Category ELISA Kit Prices $430.00, $570.00, $2,515.00, $4,520.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.156-10 ng/mL

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