Dio3

Gene Symbol	Dio3
Entrez Gene	29475
Alt Symbol	5DIII, DIOIII
Species	Rat
Gene Type	protein-coding
Description	deiodinase, iodothyronine, type III
Other Description	deiodinase, iodothyronine, type 3|type 3 DI|type III iodothyronine deiodinase|type-III 5'-deiodinase
Swissprots	P49897
Accessions	EDL97515 P49897 BM414881 U24282 AAC52241 NM_017210 NP_058906
Function	Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.
Subcellular Location	Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Endosome membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity	Neonatal skin, placenta, skeletal muscle and cerebral cortex. {ECO:0000269|PubMed:7622463}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Rat Dio3 protein - orb244709 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Rat

Rat Dio3 protein - orb246086 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Rat

Rat DIO3 Protein - abx066298 from Abbexa Category Protein Source E.coli Species Rat

Deiodinase, Iodothyronine, Type III (DIO3), Rat - 20-9142 from ARP American Research Products Category Protein Prices $569.00 Sizes 50 µg Source E.coli Species Rat

Recombinant Deiodinase, Iodothyronine, Type III (DIO3) - RPF989Ra01 from Cloud-clone Category Protein Source E.coli Species Rat

Recombinant Rat Type III iodothyronine deiodinase(Dio3) - CSB-YP344617RA CSB-BP344617RA CSB-MP344617RA from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Rat

Recombinant Rat Type III iodothyronine deiodinase(Dio3) - CSB-EP344617RA from Cusabio Category Protein Source Yeast Species Rat

Deiodinase, Iodothyronine, Type III (DIO3) - RPU141163 from Biomatik Category Protein Prices $275.00, $550.00, $825.00 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Rat

Recombinant Rat DIO3 Protein - DIO3-1870R from Creative Biomart Category Protein Source Mammalian Cells Species Rat

Dio3 Recombinant Protein (OPCA02085) - OPCA02085 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Rat

Dio3 Recombinant Protein (OPCA02912) - OPCA02912 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Rat

Recombinant Deiodinase, Iodothyronine, Type III (DIO3) - RPU41163 from Biomatik Category Protein Prices $200.00, $430.00, $656.00, $820.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Rat

DIO3 Recombinant Protein (OPCD02738) - OPCD02738 from Aviva Systems Biology Category Protein Source E.coli Species Rat

Recombinant rat Type III iodothyronine deiodinase - AP71088 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Rat

Recombinant rat Type III iodothyronine deiodinase - AP72941 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source Yeast Species Rat

Deiodinase, Iodothyronine, Type III (DIO3), Recombinant Protein - MBS2009300 from MyBioSource Category Protein Prices $200.00, $440.00, $690.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Rat

Recombinant Rat DIO3 Protein (37-278 aa), His-tagged - DIO3-1603R from Creative Biomart Category Protein Source Yeast Species Rat

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