IER3

Gene Symbol	IER3
Entrez Gene	8870
Alt Symbol	DIF-2, DIF2, GLY96, IEX-1, IEX-1L, IEX1, PRG1
Species	Human
Gene Type	protein-coding
Description	immediate early response 3
Other Description	PACAP-responsive gene 1 protein|anti-death protein|differentiation-dependent gene 2 protein|expressed in pancreatic carcinoma|gly96, mouse, homolog of|immediate early protein GLY96|immediate early response 3 protein|immediately early gene X-1|protein DIF-2|radiation-inducible immediate-early gene IEX-1
Swissprots	Q93044 P46695 Q5SU30 Q92691
Accessions	AAC72344 BAB63319 BAC54933 BAE78619 BAF31268 CAA65304 CAA76350 EAX03329 EAX03330 EAX03331 P46695 AF039067 AAC32558 AF083421 AAC33793 AJ227914 AK222588 BAD96308 AK314162 BAG36846 BC000844 AAH00844 BC005080 AAH05080 BM915952 BT006703 AAP35349 DA893782 S81914 AAB36278 Y14551 CAA74886 NM_003897 NP_003888 NM_052815
Function	May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A- PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment. {ECO:0000269|PubMed:12356731, ECO:0000269|PubMed:16456541, ECO:0000269|PubMed:22565310}.
Subcellular Location	Membrane {ECO:0000269|PubMed:12356731}; Single-pass type II membrane protein {ECO:0000269|PubMed:12356731}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IER3 cDNA (ANA10845) - ANA10845 from Aviva Systems Biology Prices $189.00 Sizes 1 µg Accession BC000844

IER3 cDNA (ANA11137) - ANA11137 from Aviva Systems Biology Prices $189.00 Sizes 1 µg Accession BC000844

Human IER3 ORF Clone(NM_003897.3) - CDCL166792 from Creative Biomart Species Human Accession NM_003897.3

Human IER3 Gene cDNA Clone (full-length ORF Clone) - HG16174-G from Sino Biological Species Human Accession NM_003897.3

Human IER3 Gene cDNA Clone (full-length ORF Clone), expression ready, N-HA-tagged - HG16174-NY from Sino Biological Species Human Accession NM_003897.3

Human IER3 Gene cDNA Clone (full-length ORF Clone), expression ready, C-His-tagged - HG16174-CH from Sino Biological Species Human Accession NM_003897.3

Human IER3 natural ORF mammalian expression plasmid, C-OFPSpark tag - HG16174-ACR from Sino Biological Species Human Accession NM_003897.3

Human IER3 Gene cDNA Clone (full-length ORF Clone), expression ready, N-FLAG-tagged - HG16174-NF from Sino Biological Species Human Accession NM_003897.3

Human IER3 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG16174-UT from Sino Biological Species Human Accession NM_003897.3

Human IER3 Gene cDNA Clone (full-length ORF Clone), expression ready, C-FLAG-tagged - HG16174-CF from Sino Biological Species Human Accession NM_003897.3

Human IER3 Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-tagged - HG16174-NM from Sino Biological Species Human Accession NM_003897.3

Human IER3 Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-tagged - HG16174-CM from Sino Biological Species Human Accession NM_003897.3

Human IER3 Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-tagged - HG16174-NH from Sino Biological Species Human Accession NM_003897.3

Human IER3 Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-tagged - HG16174-CY from Sino Biological Species Human Accession NM_003897.3

Human IER3 Gene cDNA Clone (full-length ORF Clone), expression ready, C-GFPSpark-tagged - HG16174-ACG from Sino Biological Species Human Accession NM_003897.3

Human IER3 ORF clone (NM_003897.3) - CDCL119311 from Creative biogene Species Human

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