IER3

Gene Symbol IER3
Entrez Gene 8870
Alt Symbol DIF-2, DIF2, GLY96, IEX-1, IEX-1L, IEX1, PRG1
Species Human
Gene Type protein-coding
Description immediate early response 3
Other Description PACAP-responsive gene 1 protein|anti-death protein|differentiation-dependent gene 2 protein|expressed in pancreatic carcinoma|gly96, mouse, homolog of|immediate early protein GLY96|immediate early response 3 protein|immediately early gene X-1|protein DIF-2|radiation-inducible immediate-early gene IEX-1
Swissprots Q93044 P46695 Q5SU30 Q92691
Accessions AAC72344 BAB63319 BAC54933 BAE78619 BAF31268 CAA65304 CAA76350 EAX03329 EAX03330 EAX03331 P46695 AF039067 AAC32558 AF083421 AAC33793 AJ227914 AK222588 BAD96308 AK314162 BAG36846 BC000844 AAH00844 BC005080 AAH05080 BM915952 BT006703 AAP35349 DA893782 S81914 AAB36278 Y14551 CAA74886 NM_003897 NP_003888 NM_052815
Function May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A- PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment. {ECO:0000269|PubMed:12356731, ECO:0000269|PubMed:16456541, ECO:0000269|PubMed:22565310}.
Subcellular Location Membrane {ECO:0000269|PubMed:12356731}; Single-pass type II membrane protein {ECO:0000269|PubMed:12356731}.

IEX-1 (C-20) - sc-8454 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
IEX-1 (C-20): sc-8454. Immunoperoxidase staining of formalin fixed, paraffin-embedded human bronchus tissue showing cytoplasmic staining of respiratory epithelial cells.

IEX-1 (FL-156) - sc-33171 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
IEX-1 (FL-156): sc-33171. Western blot analysis of IEX-1 expression in C32 whole cell lysate.

IEX-1 (N-17) - sc-8453 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
IEX-1 (N-17): sc-8453. Western blot analysis of IEX-1 expression in non-transfected: sc-117752 (A) and human IEX-1 transfected: sc-110039 (B) 293T whole cell lysates.

Anti-IEX1 antibody - ab65152 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human adrenal tissue, staining IEX1 with ab65152 at 5 µg/ml.

Anti-IEX1 antibody - N-terminal - ab170453 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Flow cytometric analysis of A549 cells (green) compared to a negative control cell (blue) using ab170453 at a 1/10 dilution. FITC conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Anti-IER3 / IEX-1 Antibody - LS-C121235 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-IER3 / IEX-1 Antibody (aa38-65) - LS-C165117 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
IER3 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-IER3 / IEX-1 Antibody (Internal) IHC-plus™ - LS-B1360 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-IEX1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1360 concentration 5 ug/ml.

Anti-IER3 / IEX-1 Antibody (aa38-65, AP) - LS-C259017 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IER3 / IEX-1 Antibody (aa38-65, APC) - LS-C259019 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IER3 / IEX-1 Antibody (aa38-65, Biotin) - LS-C259020 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IER3 / IEX-1 Antibody (aa38-65, FITC) - LS-C259021 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IER3 / IEX-1 Antibody (aa38-65, PE) - LS-C259023 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IER3 / IEX-1 Antibody (aa38-65, Azide-free, HRP) - LS-C259024 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IER3 / IEX-1 Antibody (aa45-73) - LS-C322148 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

IER3 Antibody - NBP1-76802 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: IER3 Antibody [NBP1-76802] - Analysis of IEX-1 in mouse skin tissue lysate with IEX-1 antibody at (A) 1 and (B) 2 ug/mL..

IER3 Antibody - NBP2-38513 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: IER3 Antibody [NBP2-38513] - Staining of human urinary bladder shows distinct cytoplasmic positivity in urothelial cells.

IER3 Antibody - NBP1-48368 from Novus Biologicals

Prices $329.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IEX-1 antibody produced in rabbit - PRS4247 from Sigma-Aldrich

Prices $347.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-IEX-1: <B>Cat. No. PRS4247</B> Immunohistochemistry of IEX-1 in human liver tissue with IEX-1 antibody at 2.5 μg/mL.

ANTI-IER3(N-TERMINAL) antibody produced in rabbit - SAB1307239 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-IER3 (N-term): <B>Cat. No. SAB1307239</B>: IER3 Antibody (N-term) western blot analysis in A549 cell line lysates (35 μg/lane).

Anti-IER3 antibody produced in rabbit - SAB2900271 from Sigma-Aldrich

Prices $464.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-IER3: <B>Cat. No.SAB2900271</B>: Adrenal: Formalin-Fixed Paraffin-Embedded (FFPE).

IER3-Antibody-N-term - AP11790a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
IER3 Antibody (N-term) (Cat. #AP11790a) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the IER3 antibody detected the IER3 protein (arrow).

IEX1 antibody - GTX60211 from GeneTex

Prices $319.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Anti-IEX1 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX60211

IER3 Antibody - N-terminal region (OAAB08033) - OAAB08033 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

IEX 1 antibody - orb74847 from Biorbyt

Prices $723.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of human brain tissue lysate at (A) 2 and (B) 4 ug/mL using IEX 1 antibody
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