IER3

Gene Symbol	IER3
Entrez Gene	8870
Alt Symbol	DIF-2, DIF2, GLY96, IEX-1, IEX-1L, IEX1, PRG1
Species	Human
Gene Type	protein-coding
Description	immediate early response 3
Other Description	PACAP-responsive gene 1 protein|anti-death protein|differentiation-dependent gene 2 protein|expressed in pancreatic carcinoma|gly96, mouse, homolog of|immediate early protein GLY96|immediate early response 3 protein|immediately early gene X-1|protein DIF-2|radiation-inducible immediate-early gene IEX-1
Swissprots	Q93044 P46695 Q5SU30 Q92691
Accessions	AAC72344 BAB63319 BAC54933 BAE78619 BAF31268 CAA65304 CAA76350 EAX03329 EAX03330 EAX03331 P46695 AF039067 AAC32558 AF083421 AAC33793 AJ227914 AK222588 BAD96308 AK314162 BAG36846 BC000844 AAH00844 BC005080 AAH05080 BM915952 BT006703 AAP35349 DA893782 S81914 AAB36278 Y14551 CAA74886 NM_003897 NP_003888 NM_052815
Function	May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A- PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment. {ECO:0000269|PubMed:12356731, ECO:0000269|PubMed:16456541, ECO:0000269|PubMed:22565310}.
Subcellular Location	Membrane {ECO:0000269|PubMed:12356731}; Single-pass type II membrane protein {ECO:0000269|PubMed:12356731}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IEX1 full length protein - ab152929 from Abcam Category Protein Source Wheat germ Species Human

Human IEX1 protein fragment - ab156719 from Abcam Category Protein Source E. coli Species Human

Human IEX1 protein fragment - ab152930 from Abcam Category Protein Source Wheat germ Species Human

IER3 / IEX-1 Antibody Blocking Peptide - LS-E1221 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IER3 / IEX-1 Antibody Blocking Peptide - LS-E30357 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

IER3 Partial Recombinant Protein - H00008870-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

IER3 Recombinant Protein - H00008870-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 2 µg Species Human

Recombinant Human IER3 Protein - NBP2-23130 from Novus Biologicals Category Protein Prices $269.00 Sizes 20 µg Source E.coli Species Human

IER3 Blocking Peptide - NBP1-76802PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

IER3-Antibody-N-term-Blocking-peptide - BP11790a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

IER3 Protein Lysate (APL10845) - APL10845 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

Human IER3 protein - orb191300 from Biorbyt Category Protein Prices $230.00, $442.00, $1,811.00 Sizes 2 μg, 10 μg, 100 μg Source E. coli Species Human

IER3 protein (His tag) - 80R-2838 from Fitzgerald Category Protein Prices $275.00 Sizes 20 µg Source E.coli

IER3 / IEX1 (1-82, His-tag) - AR50957PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 100 µg Source E. coli Species Human

IER3 / IEX1 (1-82, His-tag) - AR50957PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 20 µg Source E. coli Species Human

IER3 / IEX1 - H00008870-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

IER3 / IEX1 - H00008870-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

IER3 / IEX1 - H00008870-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

IER3 / IEX1 - H00008870-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

IER3 / IEX1 - H00008870-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

IER3 / IEX1 Control Peptide - AP30400CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

IER3, 1-82 aa, Human, His tag, E.coli - 01-P2133 from ARP American Research Products Category Protein Prices $139.00, $369.00, $849.00 Sizes 5 µg, 20 µg, 100 µg Species Human

IEX-1 Peptide - 4247P from ProSci Category Peptide Species Human

IER3 fusion protein - ag12973 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

IER3 fusion protein - ag12972 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

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