IER3

Gene Symbol IER3
Entrez Gene 8870
Alt Symbol DIF-2, DIF2, GLY96, IEX-1, IEX-1L, IEX1, PRG1
Species Human
Gene Type protein-coding
Description immediate early response 3
Other Description PACAP-responsive gene 1 protein|anti-death protein|differentiation-dependent gene 2 protein|expressed in pancreatic carcinoma|gly96, mouse, homolog of|immediate early protein GLY96|immediate early response 3 protein|immediately early gene X-1|protein DIF-2|radiation-inducible immediate-early gene IEX-1
Swissprots Q93044 P46695 Q5SU30 Q92691
Accessions AAC72344 BAB63319 BAC54933 BAE78619 BAF31268 CAA65304 CAA76350 EAX03329 EAX03330 EAX03331 P46695 AF039067 AAC32558 AF083421 AAC33793 AJ227914 AK222588 BAD96308 AK314162 BAG36846 BC000844 AAH00844 BC005080 AAH05080 BM915952 BT006703 AAP35349 DA893782 S81914 AAB36278 Y14551 CAA74886 NM_003897 NP_003888 NM_052815
Function May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A- PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment. {ECO:0000269|PubMed:12356731, ECO:0000269|PubMed:16456541, ECO:0000269|PubMed:22565310}.
Subcellular Location Membrane {ECO:0000269|PubMed:12356731}; Single-pass type II membrane protein {ECO:0000269|PubMed:12356731}.

IEX-1 CRISPR/Cas9 KO Plasmid (h) - sc-403107 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IEX-1 HDR Plasmid (h) - sc-403107-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IEX-1 Double Nickase Plasmid (h) - sc-403107-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IEX-1 Double Nickase Plasmid (h2) - sc-403107-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IEX-1 CRISPR Activation Plasmid (h) - sc-403107-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IEX-1 CRISPR Activation Plasmid (h2) - sc-403107-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IEX-1 Lentiviral Activation Particles (h) - sc-403107-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IEX-1 Lentiviral Activation Particles (h2) - sc-403107-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IEX-1 siRNA (h) - sc-43859 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IEX-1 shRNA Plasmid (h) - sc-43859-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IEX-1 shRNA (h) Lentiviral Particles - sc-43859-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU108141 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10450 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10450 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06151 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06151

IER3 siRNA (Human) - CRH5858 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IER3 - MBS8233545 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human IER3 (NM_003897.3) - SHH316697 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human IER3(NM_003897.3) - SHL165340 from Creative biogene

Category siRNA
Species Reactivities Human

IER3 shRNA Plasmid (Human) - CHH5858 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

IER3 miRNA 3'UTR clone - MiUTR1H-04794 from Creative biogene

Species Reactivities Human
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