GUCY2C

Gene Symbol	GUCY2C
Entrez Gene	2984
Alt Symbol	DIAR6, GUC2C, MECIL, MUCIL, STAR
Species	Human
Gene Type	protein-coding
Description	guanylate cyclase 2C
Other Description	GC-C|STA receptor|guanylyl cyclase C|hSTAR|heat stable enterotoxin receptor|heat-stable enterotoxin receptor|intestinal guanylate cyclase
Swissprots	P25092 B2RMY6
Accessions	AAC50381 CCO13742 CDM22032 EAW96324 P25092 AK310034 AW848739 BC136544 AAI36545 BC136545 AAI36546 M73489 AAA36655 S57551 AAB19934 XM_011520631 XP_011518933 NM_004963 NP_004954
Function	Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptides guanylin and uroguanylin.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:23269669}; Single-pass type I membrane protein {ECO:0000269|PubMed:23269669}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:23269669}; Single-pass type I membrane protein {ECO:0000269|PubMed:23269669}. Note=The 145 kDa plasma membrane form of GC-C contains sialic acid and galactose residues, while a differencially glycosylated 130 Kda form is a high mannose form that is resident in the endoplasmic reticulum and may serve as the precursor for the cell surface form.
Top Pathways	Purine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GC-C (K-14) - sc-34426 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

GC-C (S-13) - sc-34428 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

GC-C (537) - sc-100302 from Santa Cruz Biotechnology Prices $295.00 Sizes 100 µg/ml Host Mouse Clonality Monoclonal

Anti-GUCY2C antibody - ab122404 from Abcam Prices $443.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-GUCY2C / Guanylyl Cyclase C Antibody (clone 2F3) - LS-C197385 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2F3

GUCY2C Antibody - NBP1-81788 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

GUCY2C Antibody - NB100-75627 from Novus Biologicals Host Chicken Clonality Polyclonal

GUCY2C Antibody (2H8) - H00002984-M04 from Novus Biologicals Prices $359.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone 2H8

GUCY2C Antibody (1B11) - H00002984-M02 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1B11

GUCY2C Antibody (2G7) - H00002984-M09 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2G7

GUCY2C Antibody (1E1.) - H00002984-M05 from Novus Biologicals Prices $359.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone 1E1.

GUCY2C Antibody (1E1) - H00002984-M05A from Novus Biologicals Prices $349.00 Sizes 200 µl Host Mouse Clonality Monoclonal Clone 1E1

GUCY2C Antibody (3D2) - H00002984-M08 from Novus Biologicals Prices $349.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3D2

GUCY2C Antibody (2F3) - H00002984-M01 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2F3

GUCY2C Antibody (2H8) - H00002984-M04A from Novus Biologicals Prices $349.00 Sizes 200 µl Host Mouse Clonality Monoclonal Clone 2H8

GUCY2C Antibody (3C2) - H00002984-M06 from Novus Biologicals Prices $349.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3C2

GUCY2C Antibody (3H1) - H00002984-M12 from Novus Biologicals Prices $349.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3H1

GUCY2C Antibody - H00002984-A01 from Novus Biologicals Prices $269.00 Sizes 50 µl Host Mouse Clonality Polyclonal

GUCY2C Antibody (3H3) - H00002984-M13 from Novus Biologicals Prices $349.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3H3

GUCY2C Antibody (1D11) - H00002984-M10 from Novus Biologicals Host Mouse Clonality Monoclonal Clone 1D11

GUCY2C Antibody (3D5) - H00002984-M03 from Novus Biologicals Prices $349.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3D5

ANTI-GUCY2C antibody produced in mouse - SAB1412659 from Sigma-Aldrich Prices $347.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone 1E1

ANTI-GUCY2C antibody produced in mouse - SAB1412458 from Sigma-Aldrich Prices $347.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3H6

ANTI-GUCY2C antibody produced in mouse - SAB1412457 from Sigma-Aldrich Prices $347.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3C2

ANTI-GUCY2C antibody produced in mouse - SAB1411956 from Sigma-Aldrich Prices $347.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2G7

Search more