Gene Symbol | P2RY1 |
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Entrez Gene | 5028 |
Alt Symbol | P2Y1 |
Species | Human |
Gene Type | protein-coding |
Description | purinergic receptor P2Y, G-protein coupled, 1 |
Other Description | ATP receptor|P2 purinoceptor subtype Y1|P2Y purinoceptor 1|platelet ADP receptor |
Swissprots | P47900 |
Accessions | AAB47091 CAA07339 EAW78773 P47900 AF018284 AAB94556 AK313920 BAG36641 AY136752 AAN01278 BC074784 AAH74784 BC074785 AAH74785 U42029 AAA97872 U42030 AAA97873 Z49205 CAA89066 NM_002563 NP_002554 |
Function | Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. {ECO:0000269|PubMed:9442040}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Rap1 signaling pathway, Neuroactive ligand-receptor interaction |
P2Y1 (E-1) - sc-377324 from Santa Cruz Biotechnology
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P2Y1 (A-15) - sc-15204 from Santa Cruz Biotechnology
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P2Y1 (H-120) - sc-20123 from Santa Cruz Biotechnology
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Anti-P2Y1 antibody - ab123340 from Abcam
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Anti-P2RY1 / P2Y1 Antibody (C-Terminus) - LS-C9435 from LifeSpan Bioscience
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Anti-P2RY1 / P2Y1 Antibody (aa247-257) - LS-C55222 from LifeSpan Bioscience
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Anti-P2RY1 / P2Y1 Antibody (aa345-356) - LS-C87229 from LifeSpan Bioscience
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Anti-P2RY1 / P2Y1 Antibody (aa231-260, AP) - LS-C265395 from LifeSpan Bioscience
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Anti-P2RY1 / P2Y1 Antibody (Extracellular Domain) IHC-plus⢠- LS-A387 from LifeSpan Bioscience
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Anti-P2RY1 / P2Y1 Antibody (aa231-260, APC) - LS-C265396 from LifeSpan Bioscience
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Anti-P2RY1 / P2Y1 Antibody (C-Terminus) IHC-plus⢠- LS-A389 from LifeSpan Bioscience
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Anti-P2RY1 / P2Y1 Antibody (aa231-260, Biotin) - LS-C265397 from LifeSpan Bioscience
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Anti-P2RY1 / P2Y1 Antibody (aa231-260, FITC) - LS-C265398 from LifeSpan Bioscience
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Anti-P2RY1 / P2Y1 Antibody (aa231-260, PE) - LS-C265401 from LifeSpan Bioscience
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Anti-P2RY1 / P2Y1 Antibody (aa231-260, Azide-free, HRP) - LS-C265400 from LifeSpan Bioscience
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Anti-P2RY1 / P2Y1 Antibody (aa230-260) - LS-C323741 from LifeSpan Bioscience
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Anti-P2RY1 / P2Y1 Antibody (aa180-229) - LS-C145227 from LifeSpan Bioscience
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Anti-P2RY1 / P2Y1 Antibody (aa231-260) - LS-C163318 from LifeSpan Bioscience
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Anti-P2RY1 / P2Y1 Antibody (clone 4C2) - LS-C197832 from LifeSpan Bioscience
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Anti-P2RY1 / P2Y1 Antibody (N-Terminus) IHC-plus⢠- LS-A3786 from LifeSpan Bioscience
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Anti-P2RY1 / P2Y1 Antibody (C-Terminus) IHC-plus⢠- LS-A3795 from LifeSpan Bioscience
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Anti-P2RY1 / P2Y1 Antibody (aa71-120) IHC-plus⢠- LS-B8204 from LifeSpan Bioscience
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P2Y1/P2RY1 Antibody - NBP1-82439 from Novus Biologicals
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P2Y1/P2RY1 Antibody - NLS387 from Novus Biologicals
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P2Y1/P2RY1 Antibody - NLS389 from Novus Biologicals
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