| Gene Symbol |
P2RY1
|
| Entrez Gene |
5028
|
| Alt Symbol |
P2Y1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
purinergic receptor P2Y, G-protein coupled, 1
|
| Other Description |
ATP receptor|P2 purinoceptor subtype Y1|P2Y purinoceptor 1|platelet ADP receptor
|
| Swissprots |
P47900
|
| Accessions |
AAB47091 CAA07339 EAW78773 P47900 AF018284 AAB94556 AK313920 BAG36641 AY136752 AAN01278 BC074784 AAH74784 BC074785 AAH74785 U42029 AAA97872 U42030 AAA97873 Z49205 CAA89066 NM_002563 NP_002554
|
| Function |
Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. {ECO:0000269|PubMed:9442040}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Rap1 signaling pathway, Neuroactive ligand-receptor interaction
|