Gene Symbol | P2RY1 |
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Entrez Gene | 5028 |
Alt Symbol | P2Y1 |
Species | Human |
Gene Type | protein-coding |
Description | purinergic receptor P2Y, G-protein coupled, 1 |
Other Description | ATP receptor|P2 purinoceptor subtype Y1|P2Y purinoceptor 1|platelet ADP receptor |
Swissprots | P47900 |
Accessions | AAB47091 CAA07339 EAW78773 P47900 AF018284 AAB94556 AK313920 BAG36641 AY136752 AAN01278 BC074784 AAH74784 BC074785 AAH74785 U42029 AAA97872 U42030 AAA97873 Z49205 CAA89066 NM_002563 NP_002554 |
Function | Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. {ECO:0000269|PubMed:9442040}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Rap1 signaling pathway, Neuroactive ligand-receptor interaction |
Human P2Y1 full length protein - ab184017 from Abcam
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Human P2Y1 protein fragment - ab152586 from Abcam
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P2RY1 / P2Y1 Antibody Blocking Peptide - LS-E3415 from LifeSpan Bioscience
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P2RY1 / P2Y1 Antibody Blocking Peptide - LS-E28814 from LifeSpan Bioscience
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P2RY1 / P2Y1 Antibody Blocking Peptide - LS-E28815 from LifeSpan Bioscience
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P2RY1 / P2Y1 Antibody Blocking Peptide - LS-E28830 from LifeSpan Bioscience
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P2RY1 / P2Y1 Antibody Blocking Peptide - LS-E28834 from LifeSpan Bioscience
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P2RY1 / P2Y1 Antibody Blocking Peptide - LS-E18466 from LifeSpan Bioscience
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P2RY1 / P2Y1 Antibody Blocking Peptide - LS-E18467 from LifeSpan Bioscience
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P2RY1 / P2Y1 Antibody Blocking Peptide - LS-E26537 from LifeSpan Bioscience
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P2RY1 / P2Y1 Antibody Blocking Peptide - LS-E26538 from LifeSpan Bioscience
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Recombinant Human P2Y1/P2RY1 Protein - H00005028-Q01 from Novus Biologicals
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P2RY1-Antibody-Center-Blocking-Peptide - BP14591c from Abgent, a WuXi AppTec company
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P2ry1 Blocking Peptide - 33R-9867 from Fitzgerald
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P2Y1 Peptide - AC21-1373-P from Abcore
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P2Y1 Peptide - AC21-1374-P from Abcore
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P2RY1 / P2Y1 - H00005028-G01 from Acris Antibodies
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P2RY1 / P2Y1 - H00005028-Q01-10 from Acris Antibodies
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P2RY1 / P2Y1 - H00005028-Q01-25 from Acris Antibodies
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P2RY1 / P2Y1 Control Peptide - SP4481CP from Acris Antibodies
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P2RY1 Peptide - 46-123P from ProSci
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Purinergic Receptor Peptide - 46-883P from ProSci
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P2RY1 fusion protein - ag12762 from Proteintech Group
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P2RY1 fusion protein - Ag12992 from Proteintech Group
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Recombinant Purinergic Receptor P2Y, G Protein Coupled 1 (P2RY1) - RPG079Hu01 from Uscn Life Science Inc.
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