ELOVL6

Gene Symbol ELOVL6
Entrez Gene 79071
Alt Symbol FACE, FAE, LCE
Species Human
Gene Type protein-coding
Description ELOVL fatty acid elongase 6
Other Description 3-keto acyl-CoA synthase ELOVL6|ELOVL FA elongase 6|ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)|elongation of very long chain fatty acids protein 6|fatty acid elongase 2|fatty acyl-CoA elongase|hELO2|long-chain fatty-acyl elongase|very-long-chain 3-oxoacyl-CoA synthase 6
Swissprots Q4W5L0 Q9H5J4 Q8NCD1
Accessions AAY40928 EAX06258 EAX06259 EAX06260 Q9H5J4 AK027031 BAB15632 AK074813 BAC11225 AK074882 BC001305 AAH01305 BE539688 BP278053 BP314858 DB368351 H65618 XM_011532233 XP_011530535 XM_011532234 XP_011530536 XM_011532235 XP_011530537 NM_001130721 NP_001124193 NM_024090 NP_076995
Function Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. {ECO:0000269|PubMed:20937905}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:20937905}; Multi-pass membrane protein {ECO:0000255}.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:20937905}.
Top Pathways Fatty acid elongation, Biosynthesis of unsaturated fatty acids, Fatty acid metabolism

ELOVL6 (H-120) - sc-135005 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ELOVL6 (H-120): sc-135005. Western blot analysis of ELOVL6 expression in mouse brain tissue extract.

ELOVL6 (Q-14) - sc-54885 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ELOVL6 antibody - ab69857 from Abcam

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-ELOVL6 antibody (ab69857) at 1 µg/mlLane 2 : Anti-ELOVL6 antibody (ab69857) at 2 µg/mlLane 1 : Human brain tissue lysateLane 2 : Human brain tissue lysateLysates/proteins at 15 µg per lane.

Anti-ELOVL6 antibody - ab115194 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-ELOVL6 antibody (ab115194) at 1 µg/mlLane 2 : Anti-ELOVL6 antibody (ab115194) at 2 µg/mlLane 1 : Human brain tissue lysateLane 2 : Human brain tissue lysate

Anti-ELOVL6 antibody - ab78665 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ELOVL6 antibody (ab78665) at 1 µg/mlLane 1 : Raji (Human Burkitt's lymphoma cell line) Whole Cell LysateLane 2 : WERI (Human Retinoblastoma) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-ELOVL6 Antibody (N-Terminus) IHC-plus™ - LS-B2710 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ELOVL6 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2710 concentration 5 ug/ml.

Anti-ELOVL6 Antibody (aa13-62) - LS-C291923 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ELOVL6 Antibody (N-Terminus) - LS-C151753 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ELOVL6 antibody Western Blot of Placenta.

Anti-ELOVL6 Antibody (C-Terminus) - LS-C151752 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ELOVL6 antibody Western Blot of Jurkat.

Anti-ELOVL6 Antibody - LS-C332605 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using ELOVL6 antibody.

Anti-ELOVL6 Antibody (aa32-58) - LS-C99246 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with ELOVL6 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

ELOVL6 Antibody - NBP1-82082 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: ELOVL6 Antibody [NBP1-82082] - Staining of human pancreas shows moderate cytoplasmic positivity in exocrine pancreas.

ELOVL6 Polyclonal Antibody - bs-7055R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ANTI-ELOVL6(N-TERMINAL) antibody produced in rabbit - SAB1307199 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ELOVL6 (N-term): <B>Cat. No. SAB1307199</B>: Western blot analysis of ELOVL6 Antibody (N-term) in Mouse liver tissue lysates (35 μg/lane).

Anti-ELOVL6 antibody produced in rabbit - HPA042355 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ELOVL6: <B>Cat. No. HPA042355</B>: Immunohistochemical staining of human colon shows moderate cytoplasmic and nuclear positivity in glandular cells.

Anti-ELOVL6 antibody produced in rabbit - SAB2900754 from Sigma-Aldrich

Prices $465.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ELOVL6 (N-Terminus), antibody produced in rabbit: <B>Cat. No. SAB2900754</B>: Anti-ELOVL6 antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 μg/mL.

ELOVL6 antibody - C-terminal region (ARP64565_P050) - ARP64565_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ELOVL6 antibody - N-terminal region (ARP64566_P050) - ARP64566_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ELOVL6 Antibody - N-terminal region (OAAB03516) - OAAB03516 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

ELOVL6-Antibody-N-term - AP6524a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of ELOVL6 antibody (N-term) (Cat.# AP6524a) in mouse liver tissue lysates (35ug/lane). ELOVL6 (arrow) was detected using the purified Pab.

Elovl6 antibody - GTX48702 from GeneTex

Prices $289.00
Sizes 50 μg
Anti-Elovl6 antibody used in Immunohistochemistry. GTX48702

ELOVL6 antibody - GTX85403 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-ELOVL6 antibody used in Immunohistochemistry. GTX85403

ELOVL6 antibody, N-term - GTX81872 from GeneTex

Prices $319.00
Sizes 400 μl
Host Rabbit
Clonality Polyclonal
Anti-ELOVL6 antibody, N-term used in Flow cytometry/FACS. GTX81872

ELOVL6 Antibody (OAAF03640) - OAAF03640 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

ELOVL6 Antibody (OAAF06354) - OAAF06354 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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