ELOVL6

Gene Symbol	ELOVL6
Entrez Gene	79071
Alt Symbol	FACE, FAE, LCE
Species	Human
Gene Type	protein-coding
Description	ELOVL fatty acid elongase 6
Other Description	3-keto acyl-CoA synthase ELOVL6|ELOVL FA elongase 6|ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)|elongation of very long chain fatty acids protein 6|fatty acid elongase 2|fatty acyl-CoA elongase|hELO2|long-chain fatty-acyl elongase|very-long-chain 3-oxoacyl-CoA synthase 6
Swissprots	Q4W5L0 Q9H5J4 Q8NCD1
Accessions	AAY40928 EAX06258 EAX06259 EAX06260 Q9H5J4 AK027031 BAB15632 AK074813 BAC11225 AK074882 BC001305 AAH01305 BE539688 BP278053 BP314858 DB368351 H65618 XM_011532233 XP_011530535 XM_011532234 XP_011530536 XM_011532235 XP_011530537 NM_001130721 NP_001124193 NM_024090 NP_076995
Function	Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. {ECO:0000269|PubMed:20937905}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:20937905}; Multi-pass membrane protein {ECO:0000255}.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:20937905}.
Top Pathways	Fatty acid elongation, Biosynthesis of unsaturated fatty acids, Fatty acid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ELOVL6 peptide - ab114079 from Abcam Category Peptide Prices $176.00 Sizes 50 µg

Human ELOVL6 peptide - ab100823 from Abcam Category Peptide

ELOVL6 Antibody Blocking Peptide - LS-E23536 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ELOVL6 Antibody Blocking Peptide - LS-E23537 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ELOVL6 Antibody Blocking Peptide - LS-E8261 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ELOVL6 Antibody Blocking Peptide - LS-E30487 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ELOVL6-Antibody-N-term-Blocking-Peptide - BP6524a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ELOVL6 Peptide - GTX85403-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

ELOVL6 peptide - orb218640 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Cat

ELOVL6 Blocking Peptide - abx063971 from Abbexa Category Peptide Species Human, Mouse, Rat, Chicken

ELOVL6 Control Peptide - AP30311CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

ELOVL6 Peptide - 4571P from ProSci Category Peptide Species Human

ELOVL6 fusion protein - Ag14163 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

ELOVL6 fusion protein - Ag16820 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human ELOVL6, GST-tagged - ELOVL6-12422H from Creative Biomart Category Protein Source E.coli Species Human

ELOVL6 Blocking Peptide - CBP2777 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Chicken

ELOVL6 Recombinant Protein Antigen - NBP1-82082PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ELOVL6 Peptide, Human - M34GP04880H from Creative Peptides Category Peptide Source Synthetic. Species Human

Elongation of very long chain fatty acids protein 6 (ELOVL6), Recombinant Protein - MBS7014226 from MyBioSource Category Protein Prices $1,080.00, $2,065.00, $3,275.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

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