MAP4K1

Gene Symbol	MAP4K1
Entrez Gene	11184
Alt Symbol	HPK1
Species	Human
Gene Type	protein-coding
Description	mitogen-activated protein kinase kinase kinase kinase 1
Other Description	MAPK/ERK kinase kinase kinase 1|MEK kinase kinase 1|MEKKK 1|hematopoietic progenitor kinase 1
Swissprots	Q92918
Accessions	EAW56799 EAW56800 EAW56801 EAW56802 Q92918 AA995240 AK303267 BAG64349 AW137524 BC148359 AAI48360 BC152994 AAI52995 BX345201 HY074876 U66464 AAB97983 XM_011526403 XP_011524705 XM_011526404 XP_011524706 NM_001042600 NP_001036065 NM_007181 NP_009112
Function	Serine/threonine-protein kinase, which may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation. Able to autophosphorylate. {ECO:0000269|PubMed:24362026, ECO:0000269|PubMed:8824585}.
Tissue Specificity	Expressed primarily in hematopoietic organs, including bone marrow, spleen and thymus. Also expressed at very low levels in lung, kidney, mammary glands and small intestine. {ECO:0000269|PubMed:8824585}.
Top Pathways	MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human MAP4K1 protein - ab107953 from Abcam Category Protein Prices $302.00, $352.00, $1,845.00 Sizes 5 µg, 10 µg, 100 µg Source Baculovirus infected sf9 cells Species Human

Human MAP4K1 full length protein - ab153161 from Abcam Category Protein Source Wheat germ Species Human

Human MAP4K1 peptide - ab22926 from Abcam Category Peptide Species Human

Human MAP4K1 protein fragment - ab153162 from Abcam Category Protein Source Wheat germ Species Human

MAP4K1 / HPK1 Antibody Blocking Peptide - LS-E25366 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP4K1 / HPK1 Antibody Blocking Peptide - LS-E16776 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP4K1 / HPK1 Antibody Blocking Peptide - LS-E7383 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP4K1 / HPK1 Blocking Peptide - LS-E7384 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP4K1 / HPK1 Antibody Blocking Peptide - LS-E9401 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MAP4K1 Protein - H00011184-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MAP4K1 Recombinant Protein - H00011184-P01 from Novus Biologicals Category Protein

MAP4K1 Peptide - P1586 from Novus Biologicals Category Peptide Species Human

MAP4K1 Peptide - P1584 from Novus Biologicals Category Peptide Species Human

MAP4K1 Peptide - P2967 from Novus Biologicals Category Peptide Species Human

Phospho-MAP4K1S171-Antibody-Blocking-peptide - BP3451a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

Phospho-MAP4K1T165-Antibody-Blocking-peptide - BP3449a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

MAP4K1-HPK1-Antibody-C-term-Blocking-peptide - BP7971b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MAP4K1 blocking peptide - GTX22646-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

MAP4K1 Blocking Peptide - 33R-9582 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MAP4K1 Peptide - AC21-0194-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

MAP4K1 - H00011184-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

MAP4K1 - H00011184-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MAP4K1 - H00011184-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MAP4K1 Peptide - 45-086P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

MAP4K1 fusion protein - ag20221 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

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