Gene Symbol | SLC1A3 |
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Entrez Gene | 6507 |
Alt Symbol | EA6, EAAT1, GLAST, GLAST1 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
Other Description | GLAST-1|excitatory amino acid transporter 1|sodium-dependent glutamate/aspartate transporter 1|solute carrier family 1 member 3 |
Swissprots | B2R5T3 Q4JCQ8 P43003 |
Accessions | AEZ00566 AEZ00567 CAA83507 EAW55945 EAW55946 P43003 AF070609 AK057823 AK293886 BAG57275 AK295032 BAG58087 AK295754 BAG58584 AK312304 BAG35230 AY954110 AAY28724 BC022285 BC037310 AAH37310 BC054475 AAH54475 BQ019197 D26443 BAA05462 DC320625 L19158 U03504 AAA50428 XM_005248342 XP_005248399 XM_011514084 XP_011512386 NM_001166695 NP_001160167 NM_001166696 NP_001160168 NM_001289939 NP_001276868 NM_001289940 NP_001276869 NM_004172 NP_004163 |
Function | Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia. |
Top Pathways | Glutamatergic synapse |
EAAT1 peptide - ab127026 from Abcam
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Human EAAT1 full length protein - ab132485 from Abcam
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Human EAAT1 full length protein - ab132486 from Abcam
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Human EAAT1 peptide - ab42682 from Abcam
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Human EAAT1 protein fragment - ab114209 from Abcam
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SLC1A3 / EAAT1 Antibody Blocking Peptide - LS-E28027 from LifeSpan Bioscience
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SLC1A3 / EAAT1 Antibody Blocking Peptide - LS-E28028 from LifeSpan Bioscience
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SLC1A3 / EAAT1 Antibody Blocking Peptide - LS-E29651 from LifeSpan Bioscience
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SLC1A3 / EAAT1 Antibody Blocking Peptide - LS-E29652 from LifeSpan Bioscience
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Recombinant Human EAAT1/GLAST-1/SLC1A3 Protein - H00006507-P01 from Novus Biologicals
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EAAT1/GLAST-1/SLC1A3 Partial Recombinant Protein - H00006507-Q01 from Novus Biologicals
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EAAT1/GLAST-1/SLC1A3 Peptide - NBP2-11258PEP from Novus Biologicals
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SLC1A3-Antibody-C-term-Blocking-Peptide - BP14593b from Abgent, a WuXi AppTec company
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EAAT1 Peptide - AC21-2786-P from Abcore
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EAAT1 Peptide - AC21-2787-P from Abcore
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SLC1A3 / EAAT1 - H00006507-P01 from Acris Antibodies
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SLC1A3 / EAAT1 - H00006507-P02 from Acris Antibodies
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SLC1A3 / EAAT1 - H00006507-P02-10 from Acris Antibodies
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SLC1A3 / EAAT1 - H00006507-P02-25 from Acris Antibodies
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SLC1A3 / EAAT1 - H00006507-Q01-10 from Acris Antibodies
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SLC1A3 / EAAT1 - H00006507-Q01-25 from Acris Antibodies
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SLC1A3 fusion protein - Ag14177 from Proteintech Group
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SLC1A3 fusion protein - ag3443 from Proteintech Group
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SLC1A3 fusion protein - Ag16962 from Proteintech Group
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Recombinant Human SLC1A3 - SLC1A3-26509TH from Creative Biomart
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