SLC1A3

Gene Symbol SLC1A3
Entrez Gene 6507
Alt Symbol EA6, EAAT1, GLAST, GLAST1
Species Human
Gene Type protein-coding
Description solute carrier family 1 (glial high affinity glutamate transporter), member 3
Other Description GLAST-1|excitatory amino acid transporter 1|sodium-dependent glutamate/aspartate transporter 1|solute carrier family 1 member 3
Swissprots B2R5T3 Q4JCQ8 P43003
Accessions AEZ00566 AEZ00567 CAA83507 EAW55945 EAW55946 P43003 AF070609 AK057823 AK293886 BAG57275 AK295032 BAG58087 AK295754 BAG58584 AK312304 BAG35230 AY954110 AAY28724 BC022285 BC037310 AAH37310 BC054475 AAH54475 BQ019197 D26443 BAA05462 DC320625 L19158 U03504 AAA50428 XM_005248342 XP_005248399 XM_011514084 XP_011512386 NM_001166695 NP_001160167 NM_001166696 NP_001160168 NM_001289939 NP_001276868 NM_001289940 NP_001276869 NM_004172 NP_004163
Function Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia.
Top Pathways Glutamatergic synapse

EAAT1 CRISPR/Cas9 KO Plasmid (h) - sc-400917 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EAAT1 HDR Plasmid (h) - sc-400917-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EAAT1 Double Nickase Plasmid (h) - sc-400917-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EAAT1 Double Nickase Plasmid (h2) - sc-400917-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EAAT1 CRISPR Activation Plasmid (h) - sc-400917-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EAAT1 CRISPR Activation Plasmid (h2) - sc-400917-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EAAT1 Lentiviral Activation Particles (h) - sc-400917-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EAAT1 Lentiviral Activation Particles (h2) - sc-400917-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EAAT1 siRNA (h) - sc-35253 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EAAT1 shRNA Plasmid (h) - sc-35253-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EAAT1 shRNA (h) Lentiviral Particles - sc-35253-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EAAT1/GLAST-1/SLC1A3 RNAi - H00006507-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU010991 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN19447 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19447 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SLC1A3 siRNA (Human) - CRH4402 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC1A3 - MBS8230131 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EAAT1 CRISPR/Cas9 KO Plasmid (h2) - sc-400917-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EAAT1 HDR Plasmid (h2) - sc-400917-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human Slc1a3 (NM_004172.4) - SHH408920 from Creative biogene

Category siRNA
Species Reactivities Human

SLC1A3 shRNA Plasmid (Human) - CHH4402 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLC1A3 miRNA 3'UTR clone - MiUTR4H-TG08101 from Creative biogene

Species Reactivities Human
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