RIT1

Gene Symbol RIT1
Entrez Gene 6016
Alt Symbol NS8, RIBB, RIT, ROC1
Species Human
Gene Type protein-coding
Description Ras-like without CAAX 1
Other Description GTP-binding protein Rit1|GTP-binding protein Roc1|Ric-like, expressed in many tissues|ras-like protein expressed in many tissues|ras-like without CAAX protein 1
Swissprots Q5VY90 Q5VY89 B4DQE8 O00720 O00646 Q92963
Accessions EAW53024 Q92963 AF084462 AAD13021 AF493923 AAM12637 AK298768 BAG60910 AK314239 BAG36908 BC104186 AAI04187 BC104187 AAI04188 BI916790 BM546985 BQ918446 BU674989 CR407639 CAG28567 U71203 AAB42213 U78165 AAB64246 Y07566 CAA68851 NM_001256820 NP_001243749 NM_001256821 NP_001243750 NM_006912 NP_008843
Function Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF- dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation. {ECO:0000269|PubMed:15632082, ECO:0000269|PubMed:23791108}.
Subcellular Location Cell membrane.
Tissue Specificity Expressed in many tissues.

Rit (H-40) - sc-367273 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Rit (H-40): sc-367273. Western blot analysis of Rit expression in Jurkat whole cell lysate.

Rit (N-12) - sc-19463 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Rit (14G7) - sc-58473 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Rit (14G7): sc-58473. Western blot analysis of Rit expression in non-transfected (A) and Rit transfected (B) 293 whole cell lysates.

Anti-RIT1 antibody - ab53720 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab53720 stained HepG2 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab53720, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-RIT1 antibody - ab127041 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-RIT1 antibody (ab127041) at 1/1000 dilution + A431 whole cell lysate at 30 µg

Anti-RIT1 antibody [14G7] - ab16458 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 14G7

Anti-RIT1 antibody - N-terminal - ab182310 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RIT1 antibody - N-terminal (ab182310) at 1 µg/ml + Rat heart tissue lysate at 10 µg

Anti-RIT1 Antibody - LS-C26664 from LifeSpan Bioscience

Prices $330.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RIT1 Antibody (aa40-70, APC) - LS-C217194 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RIT1 Antibody (aa40-70, AP) - LS-C217193 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RIT1 Antibody (aa40-70, Biotin) - LS-C217195 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RIT1 Antibody (aa40-70, FITC) - LS-C217196 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RIT1 Antibody (aa40-70, Azide-free, HRP) - LS-C217197 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RIT1 Antibody (aa40-70, PE) - LS-C217198 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RIT1 Antibody (aa40-70) - LS-C324687 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RIT1 Antibody (aa108-157) - LS-C145668 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RIT1 antibody LS-C145668 Western blot of 1 Cell lysate. Antibody concentration 1 ug/ml.

Anti-RIT1 Antibody (C-Terminus) - LS-C145667 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RIT1 antibody LS-C145667 Western blot of ACHN Cell lysate. Antibody concentration 1 ug/ml.

Anti-RIT1 Antibody (aa170-219) - LS-C118570 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from Jurkat cells, using RIT1 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-RIT1 Antibody (N-Terminus) - LS-C201676 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Rat Heart. Rit1 antibody dilution 1.0 ug/ml.

Anti-RIT1 Antibody (aa41-70) - LS-C162616 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
RIT1 Antibody western blot of mouse lung tissue lysates (35 ug/lane). The RIT1 antibody detected the RIT1 protein (arrow).

Anti-RIT1 Antibody - LS-C26663 from LifeSpan Bioscience

Prices $330.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot of Rit antibody (LS-C26663) on control 293 cells (1), 293 cells expressing HA-tagged Rit protein (2) and 293 cells expressing HA-tagged Rin protein (3).

Rit1 Antibody (456201) - MAB4697 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 456201
Western blot shows lysates of human brain tissue and HUVEC human umbilical vein endothelial cells. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human Rit1 Monoclonal Antibody (Catalog # MAB4697) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for Rit1 at approximately 25 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 3.

Rit1 Antibody - NBP2-20169 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RIT1 Antibody [NBP2-20169] - Sample (30 ug of whole cell lysate) A: A431 12% SDS PAGE gel, diluted at 1:1000.

Rit1 Antibody - NBP1-55536 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: RIT1 Antibody [NBP1-55536] - Analysis of extracts from Jurkat cells, using RIT1 Antibody. The lane on the right is treated with the synthesized peptide.

Rit1 Antibody - H00006016-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: RIT1 Antibody [H00006016-A01] - 1 polyclonal antibody (A01), Lot # 050914JC01 Western Blot analysis of RIT1 expression in HepG2 ( Cat # L019V1 ).
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