Gene Symbol | RIT1 |
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Entrez Gene | 6016 |
Alt Symbol | NS8, RIBB, RIT, ROC1 |
Species | Human |
Gene Type | protein-coding |
Description | Ras-like without CAAX 1 |
Other Description | GTP-binding protein Rit1|GTP-binding protein Roc1|Ric-like, expressed in many tissues|ras-like protein expressed in many tissues|ras-like without CAAX protein 1 |
Swissprots | Q5VY90 Q5VY89 B4DQE8 O00720 O00646 Q92963 |
Accessions | EAW53024 Q92963 AF084462 AAD13021 AF493923 AAM12637 AK298768 BAG60910 AK314239 BAG36908 BC104186 AAI04187 BC104187 AAI04188 BI916790 BM546985 BQ918446 BU674989 CR407639 CAG28567 U71203 AAB42213 U78165 AAB64246 Y07566 CAA68851 NM_001256820 NP_001243749 NM_001256821 NP_001243750 NM_006912 NP_008843 |
Function | Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF- dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation. {ECO:0000269|PubMed:15632082, ECO:0000269|PubMed:23791108}. |
Subcellular Location | Cell membrane. |
Tissue Specificity | Expressed in many tissues. |
Human RIT1 protein fragment - ab159352 from Abcam
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RIT1-Antibody-N-term-Blocking-Peptide - BP14501a from Abgent, a WuXi AppTec company
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RIT1 - H00006016-Q01-10 from Acris Antibodies
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RIT1 - H00006016-Q01-25 from Acris Antibodies
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RIT1 Blocking Peptide - CBP2011 from Cohesion Biosciences
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Rit1 (W204) Peptide - BS1317P from Bioworld Technology
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Recombinant Human GTP-binding protein Rit1(RIT1) - CSB-YP846116HU CSB-EP846116HU CSB-BP846116HU CSB-MP846116HU from Cusabio
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RIT1 - TP320552 from Acris Antibodies
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Rit1 Recombinant Protein Antigen - NBP2-49075PEP from Novus Biologicals
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GTP-binding protein Rit1 (RIT1), Recombinant Protein - MBS1301352 from MyBioSource
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RIT1 peptide - orb217874 from Biorbyt
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