Gene Symbol | CST1 |
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Entrez Gene | 1469 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | cystatin SN |
Other Description | cystain-SA-I|cystatin 1|cystatin SA-I|cystatin-1|cystatin-SN|cysteine proteinase inhibitor, type 2 family|salivary cystatin-SA-1 |
Swissprots | P01037 Q9UCQ6 Q96LE6 |
Accessions | AAA36115 EAX10134 P01037 BC021225 AAH21225 J03870 AAA60299 NM_001898 NP_001889 |
Function | Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well. |
Subcellular Location | Secreted {ECO:0000269|PubMed:20189825}. |
Tissue Specificity | Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in saliva, tears, urine and seminal fluid. {ECO:0000269|PubMed:20189825}. |
Top Pathways | Salivary secretion |
cystatin SA/SN (C-16) - sc-31774 from Santa Cruz Biotechnology
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cystatin SN (SN21) - sc-73885 from Santa Cruz Biotechnology
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Anti-Cystatin SN antibody - ab124281 from Abcam
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Anti-Cystatin SN antibody - ab68329 from Abcam
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Anti-CST1 / Cystatin SN Antibody (aa31-80) IHC-plus™ - LS-B5996 from LifeSpan Bioscience
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Anti-CST1 / Cystatin SN Antibody (aa21-141, Biotin) - LS-C297841 from LifeSpan Bioscience
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Anti-CST1 / Cystatin SN Antibody (aa21-141, FITC) - LS-C301915 from LifeSpan Bioscience
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Anti-CST1 / Cystatin SN Antibody - LS-C307111 from LifeSpan Bioscience
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Anti-CST1 / Cystatin SN Antibody (aa21-141) - LS-C293609 from LifeSpan Bioscience
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Cystatin SN Antibody - NBP1-55995 from Novus Biologicals
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Cystatin SN Antibody [Unconjugated] - AF1285 from Novus Biologicals
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Cystatin SN Antibody - H00001469-B01P from Novus Biologicals
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Cystatin SN Antibody (MM0234-5N51) - NBP2-12255 from Novus Biologicals
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Cystatin SN Antibody [Biotin] - BAF1285 from Novus Biologicals
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Anti-CST1 antibody produced in rabbit - SAB4500520 from Sigma-Aldrich
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Anti-CST1 antibody produced in rabbit - SAB4300767 from Sigma-Aldrich
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Anti-CST1 antibody produced in mouse - SAB1405670 from Sigma-Aldrich
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Cystatin SN antibody [5N51] - GTX52687 from GeneTex
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Human Cystatin SN Antibody - MAB1285 from R&D Systems
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Human Cystatin SN MAb (Clone 213139), Mouse IgG2B - MAB1285-SP from R&D Systems
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Human Cystatin SN Antibody - AF1285 from R&D Systems
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Human Cystatin SN Affinity Purified Polyclonal Ab, Goat IgG - AF1285-SP from R&D Systems
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Human Cystatin SN Biotinylated Antibody - BAF1285 from R&D Systems
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CST1 Antibody (OAAF03544) - OAAF03544 from Aviva Systems Biology
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Anti -CST1 (Cystatin-SN, Cystain-SA-I, Cystatin-1, Salivary Cystatin-SA-1) - 125417 from USBiological Life Science
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