Gene Symbol | CST1 |
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Entrez Gene | 1469 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | cystatin SN |
Other Description | cystain-SA-I|cystatin 1|cystatin SA-I|cystatin-1|cystatin-SN|cysteine proteinase inhibitor, type 2 family|salivary cystatin-SA-1 |
Swissprots | P01037 Q9UCQ6 Q96LE6 |
Accessions | AAA36115 EAX10134 P01037 BC021225 AAH21225 J03870 AAA60299 NM_001898 NP_001889 |
Function | Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well. |
Subcellular Location | Secreted {ECO:0000269|PubMed:20189825}. |
Tissue Specificity | Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in saliva, tears, urine and seminal fluid. {ECO:0000269|PubMed:20189825}. |
Top Pathways | Salivary secretion |
Human-CST1-cDNA-Clone - DC05077 from Abgent, a WuXi AppTec company
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CST1 - MBS1274404 from MyBioSource
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Human CST1 cDNA clone(NM_001898.2) - CDFH004378 from Creative Biomart
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Human CST1 ORF clone(NM_001898.2) - CDCL183761 from Creative Biomart
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Human CST1 ORF Clone(NM_001898.2) - CDCL159948 from Creative Biomart
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Human CST1 ORF Clone(NM_001898.2) - CDCR281828 from Creative Biomart
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Human CST1 ORF Clone(NM_001898.2) - CDCR281829 from Creative Biomart
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Human CST1 ORF Clone(NM_001898.2) - CDCR281830 from Creative Biomart
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Human CST1 ORF clone(NM_001898.2) - CDCL183761 from Creative biogene
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Human CST1 ORF Clone (BC021225) - CDCS410505 from Creative biogene
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Human CST1 cDNA Clone(NM_001898.2) - CDFH004378 from Creative biogene
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Human CST1 Gene - orb92271 from Biorbyt
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