SIGLEC5

Gene Symbol SIGLEC5
Entrez Gene 8778
Alt Symbol CD170, CD33L2, OB-BP2, OBBP2, SIGLEC-5
Species Human
Gene Type protein-coding
Description sialic acid binding Ig-like lectin 5
Other Description CD33 antigen-like 2|OB-binding protein 2|obesity-binding protein 2|sialic acid-binding Ig-like lectin 5|sialic acid-binding immunoglobulin-like lectin 5
Swissprots O15389
Accessions AAF87846 AAK77223 EAW72033 O15389 AF170484 AAD50978 AK225753 BC029896 AAH29896 BX106622 DC324223 DQ892433 ABM83359 H71235 U71383 AAB70703 XM_011527438 XP_011525740 NM_003830 NP_003821
Function Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed by monocytic/myeloid lineage cells. Found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. Expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation.

Siglec-5 (H-7) - sc-377005 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Siglec-5 (H-7): sc-377005. Western blot analysis of Siglec-5 expression in non-transfected: sc-117752 (A) and human Siglec-5 transfected: sc-114461 (B) 293T whole cell lysates.

Siglec-5 (H-64) - sc-135173 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Siglec-5 (H-64): sc-135173. Western blot analysis of Siglec-5 expression in non-transfected: sc-117752 (A) and human Siglec-5 transfected: sc-114461 (B) 293T whole cell lysates.

Siglec-5 (K-19) - sc-47411 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Siglec-5 (K-19): sc-47411. Western blot analysis of Siglec-5 expression in M1 (A), AML-193 (B) and HL-60 (C) whole cell lysates.

Siglec-5/14 (C-2) - sc-374584 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Siglec-5/14 (C-2): sc-374584. Western blot analysis of Siglec-5 expression in non-transfected: sc-117752 (A) and human Siglec-5 transfected: sc-114461 (B) 293T whole cell lysates.

Siglec-5/14 (E-1) - sc-374585 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Siglec-5/14 (E-1): sc-374585. Western blot analysis of Siglec-5 expression in non-transfected: sc-117752 (A) and human Siglec-5 transfected: sc-114461 (B) 293T whole cell lysates.

Siglec-5/14 (P-18) - sc-47416 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Siglec-5/14 (P-18): sc-47416. Western blot analysis of Siglec-5 expression in non-transfected: sc-117752 (A) and human Siglec-5 transfected: sc-114461 (B) 293T whole cell lysates.

Siglec-5 (EE18W) - sc-74285 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-SIGLEC5 antibody - ab198000 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue labeling SIGLEC5 using ab198000 at 1/30 dilution.

Anti-SIGLEC5 antibody - ab38582 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SIGLEC5 antibody (ab38582) at 1/100 dilution + Mouse liver tissue lysate

Anti-SIGLEC5 antibody - ab129805 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-SIGLEC5 antibody (ab129805) at 1/100 dilution + NCI-H460 cell lysate at 35 µg

Anti-SIGLEC5 antibody [1A5] - ab97426 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1A5
Overlay histogram showing THP1 cells stained with ab97426 (red line). The cells were fixed with 80% methanol (5 min) and incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab97426, 1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. Please note that Abcam do not have any data for use of this antibody on non-fixed cells. We welcome any customer feedback.

Anti-SIGLEC5 / CD170 Antibody (aa482-513) - LS-C97826 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SIGLEC5 Antibody western blot of SK-BR-3 cell line lysates (35 ug/lane). The SIGLEC5 antibody detected the SIGLEC5 protein (arrow).

Anti-SIGLEC5 / CD170 Antibody (aa17-434) - LS-C150060 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Detection of Siglec-5/14 in Human Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Human Siglec-5/14 Antigen Affinity-purified Polyclonal Antibody or control antibody, followed by Phycoerythrin-conjugated Anti-Goat IgG Secondary Antibody.

Anti-SIGLEC5 / CD170 Antibody (aa8-39) - LS-C97825 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with SIGLEC5 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-SIGLEC5 / CD170 Antibody (clone 194117) - LS-C150059 from LifeSpan Bioscience

Prices $385.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal
Clone 194117

Anti-SIGLEC5 / CD170 Antibody (aa103-132, AP) - LS-C217497 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC5 / CD170 Antibody (aa103-132, Biotin) - LS-C217499 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC5 / CD170 Antibody (aa103-132, Azide-free, HRP) - LS-C217500 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC5 / CD170 Antibody (aa103-132, APC) - LS-C217498 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC5 / CD170 Antibody (aa103-132, PE) - LS-C217501 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC5 / CD170 Antibody (C-Terminus, APC) - LS-C220649 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC5 / CD170 Antibody (C-Terminus, AP) - LS-C220650 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC5 / CD170 Antibody (C-Terminus, FITC) - LS-C220652 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC5 / CD170 Antibody (C-Terminus, Biotin) - LS-C220651 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC5 / CD170 Antibody (N-Terminus, AP) - LS-C220653 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Search more