SIGLEC5

Gene Symbol SIGLEC5
Entrez Gene 8778
Alt Symbol CD170, CD33L2, OB-BP2, OBBP2, SIGLEC-5
Species Human
Gene Type protein-coding
Description sialic acid binding Ig-like lectin 5
Other Description CD33 antigen-like 2|OB-binding protein 2|obesity-binding protein 2|sialic acid-binding Ig-like lectin 5|sialic acid-binding immunoglobulin-like lectin 5
Swissprots O15389
Accessions AAF87846 AAK77223 EAW72033 O15389 AF170484 AAD50978 AK225753 BC029896 AAH29896 BX106622 DC324223 DQ892433 ABM83359 H71235 U71383 AAB70703 XM_011527438 XP_011525740 NM_003830 NP_003821
Function Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed by monocytic/myeloid lineage cells. Found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. Expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation.

Siglec-5 CRISPR/Cas9 KO Plasmid (h) - sc-407462 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-5 HDR Plasmid (h) - sc-407462-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-5 Double Nickase Plasmid (h) - sc-407462-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-5 Double Nickase Plasmid (h2) - sc-407462-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-5 CRISPR Activation Plasmid (h) - sc-407462-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-5 CRISPR Activation Plasmid (h2) - sc-407462-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-5 Lentiviral Activation Particles (h) - sc-407462-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-5 Lentiviral Activation Particles (h2) - sc-407462-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-5 siRNA (h) - sc-61549 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Siglec-5 shRNA Plasmid (h) - sc-61549-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Siglec-5 shRNA (h) Lentiviral Particles - sc-61549-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU111001 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19333 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19333 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02054 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02054

SIGLEC5 siRNA (Human) - CRH5783 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SIGLEC5 - MBS8216095 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SIGLEC5 (NM_003830.3) - SHH407464 from Creative biogene

Category siRNA
Species Reactivities Human

Human SIGLEC5 siRNA - orb266285 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SIGLEC5 shRNA Plasmid (Human) - CHH5783 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SIGLEC5 miRNA 3'UTR clone - MiUTR3H-06635 from Creative biogene

Species Reactivities Human
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