Gene Symbol | SIGLEC5 |
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Entrez Gene | 8778 |
Alt Symbol | CD170, CD33L2, OB-BP2, OBBP2, SIGLEC-5 |
Species | Human |
Gene Type | protein-coding |
Description | sialic acid binding Ig-like lectin 5 |
Other Description | CD33 antigen-like 2|OB-binding protein 2|obesity-binding protein 2|sialic acid-binding Ig-like lectin 5|sialic acid-binding immunoglobulin-like lectin 5 |
Swissprots | O15389 |
Accessions | AAF87846 AAK77223 EAW72033 O15389 AF170484 AAD50978 AK225753 BC029896 AAH29896 BX106622 DC324223 DQ892433 ABM83359 H71235 U71383 AAB70703 XM_011527438 XP_011525740 NM_003830 NP_003821 |
Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed by monocytic/myeloid lineage cells. Found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. Expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation. |
Human SIGLEC5 protein fragment - ab160181 from Abcam
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SIGLEC5 / CD170 Antibody Blocking Peptide - LS-E4012 from LifeSpan Bioscience
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SIGLEC5 / CD170 Antibody Blocking Peptide - LS-E4013 from LifeSpan Bioscience
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SIGLEC5 / CD170 Antibody Blocking Peptide - LS-E4350 from LifeSpan Bioscience
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Recombinant Human Siglec-5/CD170 Protein - H00008778-Q01 from Novus Biologicals
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Siglec-5/CD170 Peptide - P0596 from Novus Biologicals
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Siglec-5/CD170 Peptide - P0595 from Novus Biologicals
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SIGLEC5-Antibody-C-term-Blocking-Peptide - BP1623b from Abgent, a WuXi AppTec company
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SIGLEC5-Antibody-N-term-Blocking-Peptide - BP1623a from Abgent, a WuXi AppTec company
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SIGLEC5-Antibody-N-term-Blocking-Peptide - BP16649a from Abgent, a WuXi AppTec company
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Recombinant Human Siglec-5 Fc Chimera, CF - 1072-SL-050 from R&D Systems
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Human SIGLEC5 protein - orb139656 from Biorbyt
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Human SIGLEC5 protein - orb139657 from Biorbyt
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Human SIGLEC5 Protein - abx069069 from Abbexa
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Human SIGLEC5 Protein - abx069068 from Abbexa
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Human SIGLEC5 Protein - abx069070 from Abbexa
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CD170 / SIGLEC5 - H00008778-Q01-10 from Acris Antibodies
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CD170 / SIGLEC5 - H00008778-Q01-25 from Acris Antibodies
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Sialic Acid Binding Ig Like Lectin 5 (SIGLEC5), Human - 20-7342 from ARP American Research Products
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Sialic Acid Binding Ig Like Lectin 5 (SIGLEC5), Human - 20-7343 from ARP American Research Products
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Sialic Acid Binding Ig Like Lectin 5 (SIGLEC5), Human - 20-7344 from ARP American Research Products
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SIGLEC5 Recombinant Protein - 96-691 from ProSci
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SIGLEC5 fusion protein - ag4101 from Proteintech Group
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SIGLEC5 fusion protein - Ag14469 from Proteintech Group
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Recombinant Human SIGLEC5, Fc tagged - SIGLEC5-7330H from Creative Biomart
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