RGS20

Gene Symbol RGS20
Entrez Gene 8601
Alt Symbol RGSZ1, ZGAP1, g(z)GAP, gz-GAP
Species Human
Gene Type protein-coding
Description regulator of G-protein signaling 20
Other Description gz-selective GTPase-activating protein|regulator of G-protein signaling 20 variant 2|regulator of G-protein signaling Z1|regulator of G-protein signalling 20|regulator of Gz-selective protein signaling 1
Swissprots Q96BG9 O76081
Accessions EAW86734 EAW86735 EAW86736 EAW86737 EAW86738 O76081 AF060877 AAC62009 AF074979 AAC62013 AF366054 AAK54122 AF366055 AAK54123 AF366056 AAK54124 AF366057 AAK54125 AF493940 AAM12654 AK094503 BAG52876 AY046538 AAL03971 BC015614 AAH15614 BC018618 BC031328 BC054867 BC063490 AAH63490 HQ257937 ADR82691 JQ308180 AFF59490 XM_011517622 XP_011515924 NM_001286673 NP_001273602 NM_001286674 NP_001273603 NM_001286675 NP_001273604 NM_003702 NP_003693 NM_170587 NP_733466 NR_104578 NR_104579
Function Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G- protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Lipid-anchor. Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm/cell membrane and the nucleus. Anchored to the membrane through palmitoylation. {ECO:0000250}.
Tissue Specificity Isoform 5 is expressed in brain at high levels in the caudate nucleus and temporal lobe.

RGS20 (C-13) - sc-48291 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RGS20 (C-13): sc-48291. Western blot analysis of RGS20 expression in non-transfected: sc-117752 (A) and human RGS20 transfected: sc-372921 (B) 293T whole cell lysates.

RGS20 (H-180) - sc-99135 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

RGS20 (M-20) - sc-48293 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RGS20 (M-20): sc-48293. Western blot analysis of RGS20 expression in C6 (A) and EOC 20 (B) whole cell lysates.

RGS20 (P-12) - sc-48295 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RGS20 (P-12): sc-48295. Western blot analysis of RGS20 expression in non-transfected: sc-117752 (A) and human RGS20 transfected: sc-372921 (B) 293T whole cell lysates.

RGS20 (P-13) - sc-48296 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RGS20 (P-13): sc-48296. Western blot analysis of RGS20 expression in U-87 MG whole cell lysate.

Anti-RGS20 antibody - ab77009 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-RGS20 antibody (ab77009) at 5 µg/ml + Recombinant fragment of human RGS20 at 0.2 µgSecondaryGoat anti-Mouse IgG (H&L)-HRP at 1/5000 dilution

Anti-RGS20 antibody - ab191500 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RGS20 antibody (ab191500) at 500 Lane 1 : HEK293T whole cell lysateLane 2 : NIH 3T3 whole cell lysateLane 3 : H9C2 whole cell lysate

Anti-RGS20 antibody - ab123007 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RGS20 antibody (ab123007) at 1 µg/ml + COLO205 cell lysate at 10 µg

Anti-RGS20 antibody - ab172228 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-RGS20 antibody (ab172228) at 1 µg/mlLane 1 : RGS20 transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateSecondaryGoat Anti-Mouse IgG at 1/2500 dilution

Anti-RGS20 / RGSZ1 Antibody (aa148-161) - LS-C147923 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-RGS20 / RGSZ1 Antibody (aa30-48) - LS-C147925 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-RGS20 / RGSZ1 Antibody (aa171-189) - LS-C147944 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-RGS20 / RGSZ1 Antibody (aa1-15) - LS-C147924 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-RGS20 / RGSZ1 Antibody - LS-C342150 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RGS20 / RGSZ1 Antibody (N-Terminus) - LS-C30925 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HepG2 Cell Lysate

Anti-RGS20 / RGSZ1 Antibody (aa59-108) - LS-C146030 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RGS20 antibody LS-C146030 Western blot of COL0205 Cell lysate. Antibody concentration 1 ug/ml.

Anti-RGS20 / RGSZ1 Antibody (aa127-176) - LS-C30647 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
RGS20 antibody LS-C30647 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-RGS20 / RGSZ1 Antibody (aa150-184) - LS-C344261 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysates from HepG2, U-87 MG cell line and human brain tissue lysate (from left to right) with RGS20 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35 ug per lane.

RGS20 Antibody - NBP1-54885 from Novus Biologicals

Prices $139.00, $299.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RGS20 Antibody [NBP1-54885] - Titration: 2.5ug/ml Positive Control: Human brain.

RGS20 Antibody - H00008601-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: RGS20 Antibody [H00008601-D01P] - Analysis of RGS20 expression in mouse spleen.

RGS20 Antibody (3E10.) - H00008601-M04 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3E10.
Western Blot: RGS20 Antibody (3E10) [H00008601-M04] - Analysis of RGS20 expression in NIH/3T3 (Cat # L018V1).

RGS20 Antibody - NBP1-54839 from Novus Biologicals

Prices $139.00, $299.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RGS20 Antibody [NBP1-54839] - HepG2 cell lysate, concentration 5.0ug/ml.

RGS20 Antibody - H00008601-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RGS20 Antibody - H00008601-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: RGS20 Antibody [H00008601-B01] - analysis of RGS20 expression in transfected 293T cell line by RGS20 MaxPab polyclonal antibody (B01). Lane 1: RGS20 transfected lysate (27.10 KDa). Lane 2: Non-transfected lysate.

RGS20 Antibody - H00008601-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: RGS20 Antibody [H00008601-B01P] - Analysis of RGS20 expression in transfected 293T cell line by RGS20 polyclonal antibody.  Lane 1: RGS20 transfected lysate(26.51 KDa). Lane 2: Non-transfected lysate.
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