TIA1

Gene Symbol TIA1
Entrez Gene 7072
Alt Symbol TIA-1, WDM
Species Human
Gene Type protein-coding
Description TIA1 cytotoxic granule-associated RNA binding protein
Other Description T-cell-restricted intracellular antigen-1|nucleolysin TIA-1 isoform p40|p40-TIA-1 (containing p15-TIA-1)
Swissprots P31483 Q96B58 Q53SS9
Accessions AAD14053 AAX93193 EAW99823 EAW99824 EAW99825 EAW99826 EAW99827 P31483 AB209211 BAD92448 AK093744 AK303345 BAG64407 BC015944 AAH15944 BM146739 CN295707 CX867570 DB136383 DR157578 M77142 XM_005264527 XP_005264584 XM_005264528 XP_005264585 XM_005264531 XP_005264588 XM_011533077 XP_011531379 XM_011533078 XP_011531380 XM_011533079 XP_011531381 XM_011533080 XP_011531382 XM_011533081 XP_011531383 XM_011533082 XP_011531384 XM_011533083 XP_011531385 XR_244955 XR_939714 XR_939715 NM_022037 NP_071320 NM_022173 NP_071505
Function Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
Subcellular Location Cytoplasmic granule. Nucleus. Note=Accumulates in cytoplasmic stress granules (SG) following cellular damage.

TIA-1 Antibody - 13980 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using TIA-1 Antibody.

TIA-1 (G-11) - sc-365349 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TIA-1 (G-11): sc-365349. Western blot analysis of TIA-1 expression in K-562 (A), Jurkat (B) and BJAB (C) whole cell lysates.

TIA-1 (G-3) - sc-166247 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TIA-1 (G-3): sc-166247. Western blot analysis of TIA-1 expression in non-transfected: sc-110760 (A) and truncated human TIA-1 transfected: sc-111880 (B) 293 whole cell lysates.

TIA-1 (N-19) - sc-34739 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TIA-1 (N-19): sc-34739. Western blot analysis of TIA-1 expression in non-transfected: sc-110760 (A) and truncated human TIA-1 transfected: sc-111880 (B) 293 whole cell lysates.

TIA-1 (C-10) - sc-166246 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TIA-1 (C-10): sc-166246. Western blot analysis of TIA-1 expression in non-transfected: sc-110760 (A) and truncated human TIA-1 transfected: sc-111880 (B) 293 whole cell lysates.

TIA-1 (C-20) - sc-1751 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TIA-1 (C-20): sc-1751. Western blot analysis of TIA-1 expression in Jurkat (A) and BJAB (B) whole cell lysates.

TIA-1/TIAR (D-9) - sc-48371 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TIA-1/TIAR (D-9): sc-48371. Western blot analysis of TIA-1 and TIAR expression in Jurkat (A) and BJAB (B) whole cell lysates.

TIA-1/TIAR (H-120) - sc-28237 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TIA-1/TIAR (H-120): sc-28237. Immunofluorescence staining of normal mouse kidney frozen section showing cytoplasmic staining.

Anti-TIA1 antibody - ab40693 from Abcam

Prices $398.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TIA1 antibody (ab40693) at 1 µg/mlLane 1 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate Lane 2 : Jurkat (Human T cell lymphoblast-like cell line) Nuclear Lysate (ab14844)Lysates/proteins at 10 µg per lane.SecondaryIRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/10000 dilutionPerformed under reducing conditions.

Anti-TIA1 antibody - ab168837 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TIA1 antibody (ab168837) at 1 µg/mlLane 1 : Jurkat whole cell lysateLane 2 : 293T whole cell lysateLane 3 : HeLa whole cell lysateLane 4 : TCMK-1 whole cell lysateLysates/proteins at 50 µg per lane.developed using the ECL technique

Anti-TIA1 antibody - ab61700 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-TIA1 antibody (ab61700) at 0.1 µg/ml + Jurkat cell lysate (35µg protein in RIPA buffer).

Anti-TIA1 antibody - ab83234 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TIA1 antibody (ab83234) at 1 µg/ml + 721_B cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-TIA1 antibody - ab89602 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-TIA1 antibody (ab89602) at 1 µg/ml + Human liver tissue lysate at 50 µg

Anti-TIA1 antibody [1C4] - ab139349 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C4
All lanes : Anti-TIA1 antibody [1C4] (ab139349) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY TIA1 cDNALysates/proteins at 5 µg per lane.

Anti-TIA1 antibody [1D7] - ab170156 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D7
Immunohistochemical analysis of paraffin-embedded Human prostate carcinoma tissue labeling TIA1 with ab170156 at 1/150 dilution.

Anti-TIA1 antibody [EPR9303] - ab138503 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9303
All lanes : Anti-TIA1 antibody [EPR9303] (ab138503) at 1/1000 dilutionLane 1 : HuT-78 cell lysatesLane 2 : K562 cell lysatesLane 3 : Jurkat cell lysatesLysates/proteins at 30 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-TIA1 antibody [EPR9304] - ab140595 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9304
All lanes : Anti-TIA1 antibody [EPR9304] (ab140595)Lane 1 : HuT-78 cell lysateLane 2 : Jurkat cell lysateLane 3 : Molt-4 cell lysateLane 4 : K562 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-TIA1 antibody [EPR9304] (HRP) - ab195526 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9304
All lanes : Anti-TIA1 antibody [EPR9304] (HRP) (ab195526) at 1/2000 dilutionLane 1 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLane 2 : MOLT4 (Human acute lymphoblastic leukemia cell line) Whole Cell LysateLane 3 : K562 (Human erythromyeloblastoid leukemia cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.developed using the ECL techniquePerformed under reducing conditions.

Anti-TIA1 antibody [TIA-1] - ab2712 from Abcam

Prices $384.00
Sizes 250 µl
Host Mouse
Clonality Monoclonal
Clone TIA-1
ab2712 at 1/3300 dilution staining monkey COS 7 cells by ICC/IF. The cells were cultured for 2 hours at 45oC and fixed in cold Methanol: Acetone 1:1 for 10 minutes. The TIA1 antibody was directly conjugated with Alexa Fluor ® 568 and after 1 hour incubation a second fixation step was performed.See Abreview

Anti-TIA-1 Antibody (C-Terminus) - LS-C30464 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal Thymus Lysate

Anti-TIA-1 Antibody (aa72-121) - LS-C101880 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TIA1 antibody LS-C101880 Western blot of 721_B cell lysate.

Anti-TIA-1 Antibody (clone 2B1) - LS-C175421 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2B1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TIA1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TIA1.

Anti-TIA-1 Antibody (aa98-110) - LS-C313295 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
WB of TIA-1 antibody. Lane 1: JURKAT Cell Lysate. Lane 2: RAJI Cell Lysate. Lane 3: CEM Cell Lysate. Lane 4: HT1080 Cell Lysate. Lane 5: K562 Cell Lysate.

Anti-TIA-1 Antibody (clone 1C4) - LS-C175431 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C4
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TIA1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TIA1.

Anti-TIA-1 Antibody - LS-C341987 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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