PARG

Gene Symbol	PARG
Entrez Gene	8505
Alt Symbol	PARG99
Species	Human
Gene Type	protein-coding
Description	poly (ADP-ribose) glycohydrolase
Other Description	mitochondrial poly(ADP-ribose) glycohydrolase|poly(ADP-ribose) glycohydrolase|poly(ADP-ribose) glycohydrolase 60 kDa isoform
Swissprots	Q86W56 Q7Z742 I6RUV3 B2RC24 B4DIU5 Q6E4P6 Q9Y4W7 A5YBK3 B4DYR4 Q6E4P7
Accessions	AAP83316 EAW93079 Q86W56 AF005043 AAB61614 AF085828 AK293735 BAH11584 AK295244 BAG58236 AK295786 BAG58607 AK301845 BAG63288 AK302560 BAG63826 AK307788 AY258587 AAP83314 AY575848 AAT66421 AY575849 AAT66422 BC012005 BC050560 AAH50560 BC052966 AAH52966 BU689347 DC408224 DQ867088 ABH85399 EF382674 ABR10027 JQ890226 AFM56043 XM_011540305 XP_011538607 XM_011540306 XP_011538608 XM_011540307 XP_011538609 XM_011540308 XP_011538610 XM_011540309 XP_011538611 XR_945850 NM_001303486 NP_001290415 NM_001303487 NP_001290416 NM_001303489 NP_001290418 NM_003631 NP_003622 NR_130168 NR_130169
Function	Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. PARG acts both as an endo- and exoglycosidase, releasing PAR of different length as well as ADP-ribose monomers. Required for retinoid acid-dependent gene transactivation, probably by dePARsylating histone demethylase KDM4D, allowing chromatin derepression at RAR-dependent gene promoters. {ECO:0000269|PubMed:23102699}.
Subcellular Location	Isoform 5: Mitochondrion matrix.
Tissue Specificity	Ubiquitously expressed. {ECO:0000269|PubMed:14527731}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PARG full length protein - ab152879 from Abcam Category Protein Source Wheat germ Species Human

Human PARG peptide - ab16386 from Abcam Category Peptide

Human PARG protein fragment - ab152880 from Abcam Category Protein Source Wheat germ Species Human

PARG Antibody Blocking Peptide - LS-E4405 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PARG Antibody Blocking Peptide - LS-E8831 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PARG Antibody Blocking Peptide - LS-E23181 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PARG Protein - H00008505-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human PARG Protein - H00008505-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

PARG Peptide - P2467 from Novus Biologicals Category Peptide Species Human

PARG-Antibody-C-term-Blocking-Peptide - BP16714b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Parg-Antibody-C-term-Blocking-Peptide - BP7283b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PARG - H00008505-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

PARG - H00008505-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PARG - H00008505-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PARG fusion protein - Ag5466 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

PARG fusion protein - ag5569 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human PARG protein, His-tagged - PARG-31H from Creative Biomart Category Protein Source Insect cells Species Human

Recombinant Human PARG protein, GST-tagged - PARG-125H from Creative Biomart Category Protein Source Wheat Germ Species Human

Recombinant Human PARG protein, GST-tagged - PARG-1529H from Creative Biomart Category Protein Source Wheat Germ Species Human

Recombinant Human PARG, GST-tagged - PARG-1528H from Creative Biomart Category Protein Source E.coli Species Human

PARG (highly active) - pro10410 from Covalab Category Protein Source Sf21 cells Species Human

Recombinant Human Poly(ADP-ribose) glycohydrolase(PARG) ,partial - CSB-YP773045HU CSB-EP773045HU CSB-BP773045HU CSB-MP773045HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Poly (ADP-ribose) glycohydrolase (PARG), partial, Recombinant Protein - MBS1294152 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PARG Protein - NBP1-89450PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

Parg-Antibody-N-term-Blocking-Peptide - BP7283a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

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