GADD45GIP1

Gene Symbol	GADD45GIP1
Entrez Gene	90480
Alt Symbol	CKBBP2, CKbetaBP2, CRIF1, MRP-L59, PLINP, PLINP-1, PRG6, Plinp1
Species	Human
Gene Type	protein-coding
Description	growth arrest and DNA-damage-inducible, gamma interacting protein 1
Other Description	39S ribosomal protein L59, mitochondrial|CKII beta binding protein 2|CKII beta-associating protein|CR6 interacting factor 1|growth arrest and DNA damage-inducible proteins-interacting protein 1|growth arrest- and DNA damage-inducible GADD45G-interacting protein|p53-responsive gene 6 protein|papillomavirus L2 interacting nuclear protein 1
Swissprots	Q9BSM6 Q8TAE8 Q8TE51 Q8IVM3 Q969P9
Accessions	EAW84335 Q8TAE8 AF412816 AAL55291 AF475095 AAM10639 AF479749 AAL85877 AI309741 AJ295986 CAC82499 AJ429498 CAD22344 BC004944 AAH04944 BC013027 AAH13027 BC013039 AAH13039 BC069200 AAH69200 BI459923 HQ447517 ADQ32003 NM_052850 NP_443082
Function	Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
Subcellular Location	Mitochondrion. Nucleus. Note=Using N- terminally tagged constructs, has been found in the nucleus (PubMed:12482659). C-terminally tagged constructs are targeted exclusively to mitochondria (PubMed:22453275). This discrepancy may be explained by masking of a potential N-terminal mitochondrial targeting signal by the tag (PubMed:22453275). {ECO:0000269|PubMed:12482659, ECO:0000269|PubMed:22453275}.
Tissue Specificity	Widely expressed. Highly expressed in the thyroid gland, heart, lymph nodes, trachea and adrenal tissues. Expressed at lower level in liver skeletal muscle, kidney, pancreas, testis, ovary and stomach. Barely detectable in adrenal adenoma and papillary thyroid cancer. {ECO:0000269|PubMed:12716909}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GADD45GIP1 full length protein - ab132831 from Abcam Category Protein Source Wheat germ Species Human

Human GADD45GIP1 protein fragment - ab113863 from Abcam Category Protein Source E. coli Species Human

GADD45GIP1 / CRIF1 Antibody Blocking Peptide - LS-E22770 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CRIF1 Recombinant Protein - H00090480-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg

Recombinant Human CRIF1 Protein - NBP1-72519 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 50 µg, 250 µg Source E. coli Species Human

Human GADD45GIP1 protein - orb168378 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

GADD45GIP1 (48-222, His-tag) - AR50105PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 250 µg Source E. coli Species Human

GADD45GIP1 (48-222, His-tag) - AR50105PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 50 µg Source E. coli Species Human

GADD45GIP1 - H00090480-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

GADD45GIP1 - H00090480-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

GADD45GIP1, 48-222 aa, Human, His tag, E.coli - 01-P1280 from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

GADD45GIP1 fusion protein - Ag9299 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

GADD45GIP1 Human - PRPS-979 from NeoScientific Category Protein Prices $65.00, $169.00, $6,760.00 Sizes 2 µg, 10 µg, 1 mg Source E.coli. Species Human

Recombinant Human GADD45GIP1 Protein - BP001940-PRO-972 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Human

GADD45GIP1, 48-222 aa , Human, His tag, E.coli - GWB-P0758D from Genway Biotech Category Protein Prices $400.00, $1,200.00 Sizes 50 μg, 250 μg Source E.coli Species Human

Recombinant Human GADD45GIP1, His-tagged - GADD45GIP1-26074TH from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human GADD45GIP1, GST-tagged - GADD45GIP1-13112H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Growth Arrest And DNA-Damage-Inducible, Gamma Interacting Protein 1, His-tagged - GADD45GIP1-1280H from Creative Biomart Category Protein

GADD45GIP1 48-222 aa - CMB-1113 from Reagent Proteins Category Protein Prices $539.00, $1,099.00 Sizes 50.00 µg, 250.00 µg Source E.coli Species Human

CRIF1 Blocking Peptide - CBP3951 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

Recombinant Human Growth arrest and DNA damage-inducible proteins-interacting protein 1(GADD45GIP1) - CSB-YP855033HU CSB-EP855033HU CSB-BP855033HU CSB-MP855033HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

GADD45GIP1, 48-222aa, Human, His tag, E.coli - ATGP1280 from ATGen Category Protein Prices $105.00, $320.00, $960.00 Sizes 10 µg, 50 µg, 250 µg Species Human

GADD45GIP1 - TP309644 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

CRIF1 Recombinant Protein Antigen - NBP2-39045PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CRIF1 Blocking Peptide - abx162444 from Abbexa Category Peptide Species Human, Mouse, Rat

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