GADD45GIP1

Gene Symbol GADD45GIP1
Entrez Gene 90480
Alt Symbol CKBBP2, CKbetaBP2, CRIF1, MRP-L59, PLINP, PLINP-1, PRG6, Plinp1
Species Human
Gene Type protein-coding
Description growth arrest and DNA-damage-inducible, gamma interacting protein 1
Other Description 39S ribosomal protein L59, mitochondrial|CKII beta binding protein 2|CKII beta-associating protein|CR6 interacting factor 1|growth arrest and DNA damage-inducible proteins-interacting protein 1|growth arrest- and DNA damage-inducible GADD45G-interacting protein|p53-responsive gene 6 protein|papillomavirus L2 interacting nuclear protein 1
Swissprots Q9BSM6 Q8TAE8 Q8TE51 Q8IVM3 Q969P9
Accessions EAW84335 Q8TAE8 AF412816 AAL55291 AF475095 AAM10639 AF479749 AAL85877 AI309741 AJ295986 CAC82499 AJ429498 CAD22344 BC004944 AAH04944 BC013027 AAH13027 BC013039 AAH13039 BC069200 AAH69200 BI459923 HQ447517 ADQ32003 NM_052850 NP_443082
Function Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
Subcellular Location Mitochondrion. Nucleus. Note=Using N- terminally tagged constructs, has been found in the nucleus (PubMed:12482659). C-terminally tagged constructs are targeted exclusively to mitochondria (PubMed:22453275). This discrepancy may be explained by masking of a potential N-terminal mitochondrial targeting signal by the tag (PubMed:22453275). {ECO:0000269|PubMed:12482659, ECO:0000269|PubMed:22453275}.
Tissue Specificity Widely expressed. Highly expressed in the thyroid gland, heart, lymph nodes, trachea and adrenal tissues. Expressed at lower level in liver skeletal muscle, kidney, pancreas, testis, ovary and stomach. Barely detectable in adrenal adenoma and papillary thyroid cancer. {ECO:0000269|PubMed:12716909}.

CRIF1 CRISPR/Cas9 KO Plasmid (h) - sc-403582 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRIF1 HDR Plasmid (h) - sc-403582-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRIF1 Double Nickase Plasmid (h) - sc-403582-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRIF1 Double Nickase Plasmid (h2) - sc-403582-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRIF1 CRISPR Activation Plasmid (h) - sc-403582-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRIF1 CRISPR Activation Plasmid (h2) - sc-403582-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRIF1 Lentiviral Activation Particles (h) - sc-403582-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRIF1 Lentiviral Activation Particles (h2) - sc-403582-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRIF1 siRNA (h) - sc-97804 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CRIF1 shRNA Plasmid (h) - sc-97804-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CRIF1 shRNA (h) Lentiviral Particles - sc-97804-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU008661 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9065 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9065 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GADD45GIP1 siRNA (Human) - CRJ3950 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GADD45GIP1 - MBS8220834 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GADD45GIP1 (NM_052850.3) - SHH298725 from Creative biogene

Category siRNA
Species Reactivities Human

Human GADD45GIP1 siRNA - orb274451 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GADD45GIP1 shRNA Plasmid (Human) - CHJ3950 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GADD45GIP1 miRNA 3'UTR clone - MiUTR3H-07420 from Creative biogene

Species Reactivities Human
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