NPR1

Gene Symbol NPR1
Entrez Gene 4881
Alt Symbol ANPRA, ANPa, GUC2A, GUCY2A, NPRA
Species Human
Gene Type protein-coding
Description natriuretic peptide receptor 1
Other Description ANP-A|ANPR-A|GC-A|NPR-A|atrial natriuretic peptide receptor 1|atrial natriuretic peptide receptor type A|atrionatriuretic peptide receptor A|guanylate cyclase A|natriuretic peptide A type receptor|natriuretic peptide receptor A|natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
Swissprots Q5SR08 Q6P4Q3 P16066 B0ZBF0
Accessions AAF01340 ACA05918 ACA05919 BAA31199 BAA77020 BAB03344 BAC53955 EAW53284 P16066 AK025024 AK298090 BAH12723 AK300446 BAG62168 BC063304 AAH63304 S72628 AAD14112 X15357 CAA33417 XM_005245218 XP_005245275 XM_006711342 XP_006711405 XM_006711343 XP_006711406 XM_011509585 XP_011507887 NM_000906 NP_000897
Function Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand. {ECO:0000269|PubMed:1672777}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways Vascular smooth muscle contraction, Oxytocin signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Purine metabolism

NPR-A (G-2) - sc-137041 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NPR-A (G-2): sc-137041. Western blot analysis of NPR-A expression in KNRK whole cell lysate.

NPR-A (G-18) - sc-34419 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NPR-A (G-18): sc-34419. Immunoperoxidase staining of formalin fixed, paraffin-embedded human fallopian tube tissue showing cytoplasmic staining of glandular cells.

NPR-A (G-14) - sc-34418 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NPR-A (G-14): sc-34418. Immunoperoxidase staining of formalin fixed, paraffin-embedded human seminal vesicle tissue showing cytoplasmic staining of glandular cells.

NPR-A (H-125) - sc-25485 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
NPR-A (H-125): sc-25485. Western blot analysis of NPR-A expression in KNRK whole cell lysate.

NPR-A (G-20) - sc-34420 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NPR-A (I-15) - sc-31632 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NPR-A (S-20) - sc-16867 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Natriuretic Peptide Receptor A antibody - ab14356 from Abcam

Prices $384.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab14356 stained MCF7 cells. The cells were 4% PFA fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab14356, 5µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Natriuretic Peptide Receptor A antibody - ab70848 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast carcinoma tissue labelling Natriuretic Peptide Receptor A with ab70848. A peroxidase-conjugated anti-rabbit IgG was used as the secondary antibody, followed by DAB staining.

Anti-Natriuretic Peptide Receptor A antibody - ab40817 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Natriuretic Peptide Receptor A antibody (ab40817) at 1 µg/ml + Kidney (Human) Tissue Lysate - adult normal tissue (ab30203) at 10 µgSecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-NPRA / NPR1 Antibody (aa29-469) - LS-C37437 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-NPRA / NPR1 Antibody (aa294-308) - LS-C37436 from LifeSpan Bioscience

Prices $365.00
Sizes 20 µl
Host Rabbit
Clonality Polyclonal

Anti-NPRA / NPR1 Antibody (aa33-473) - LS-C73160 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-NPRA / NPR1 Antibody (aa294-308) - LS-C122196 from LifeSpan Bioscience

Prices $405.00
Sizes 20 µl
Host Rabbit
Clonality Polyclonal

Anti-NPRA / NPR1 Antibody (aa29-469) - LS-C124222 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Rat
Clonality Monoclonal

Anti-NPRA / NPR1 Antibody (aa1-30, AP) - LS-C264028 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NPRA / NPR1 Antibody (aa1-30, APC) - LS-C264029 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NPRA / NPR1 Antibody (aa1-30, Azide-free, HRP) - LS-C264032 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NPRA / NPR1 Antibody (aa1-30, Biotin) - LS-C264030 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NPRA / NPR1 Antibody (aa1-30, FITC) - LS-C264031 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NPRA / NPR1 Antibody (aa1-30, PE) - LS-C264035 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NPRA / NPR1 Antibody (aa197-226, APC) - LS-C264630 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NPRA / NPR1 Antibody (aa197-226, FITC) - LS-C264632 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NPRA / NPR1 Antibody (aa197-226, AP) - LS-C264629 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NPRA / NPR1 Antibody (aa197-226, Biotin) - LS-C264631 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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