Gene Symbol | NPR1 |
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Entrez Gene | 4881 |
Alt Symbol | ANPRA, ANPa, GUC2A, GUCY2A, NPRA |
Species | Human |
Gene Type | protein-coding |
Description | natriuretic peptide receptor 1 |
Other Description | ANP-A|ANPR-A|GC-A|NPR-A|atrial natriuretic peptide receptor 1|atrial natriuretic peptide receptor type A|atrionatriuretic peptide receptor A|guanylate cyclase A|natriuretic peptide A type receptor|natriuretic peptide receptor A|natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) |
Swissprots | Q5SR08 Q6P4Q3 P16066 B0ZBF0 |
Accessions | AAF01340 ACA05918 ACA05919 BAA31199 BAA77020 BAB03344 BAC53955 EAW53284 P16066 AK025024 AK298090 BAH12723 AK300446 BAG62168 BC063304 AAH63304 S72628 AAD14112 X15357 CAA33417 XM_005245218 XP_005245275 XM_006711342 XP_006711405 XM_006711343 XP_006711406 XM_011509585 XP_011507887 NM_000906 NP_000897 |
Function | Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand. {ECO:0000269|PubMed:1672777}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Vascular smooth muscle contraction, Oxytocin signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Purine metabolism |
Human Natriuretic Peptide Receptor A full length protein - ab112332 from Abcam
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Human Natriuretic Peptide Receptor A peptide - ab28437 from Abcam
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Human Natriuretic Peptide Receptor A peptide - ab41439 from Abcam
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Human Natriuretic Peptide Receptor A peptide - ab49403 from Abcam
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Human Natriuretic Peptide Receptor A protein fragment - ab201407 from Abcam
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NPRA / NPR1 Antibody Blocking Peptide - LS-E2948 from LifeSpan Bioscience
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Recombinant Human NPRA/NPR1 Protein - H00004881-Q01 from Novus Biologicals
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NPR-1/Natriuretic Peptide Receptor A Peptide - P3113 from Novus Biologicals
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Natriuretic-Peptide-Receptor-A-Antibody-N-term-Blocking-peptide - BP8111a from Abgent, a WuXi AppTec company
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Human NPR1 protein - orb245947 from Biorbyt
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Human NPR1 protein - orb244412 from Biorbyt
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Human NPR-A Protein - abx060738 from Abbexa
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NPR1 / ANPRA - H00004881-Q01-10 from Acris Antibodies
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NPR1 / ANPRA - H00004881-Q01-25 from Acris Antibodies
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Human NPR-A (a.a. 294-308) Peptide - 227-10132 from RayBiotech
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Human NPR-A (a.a. 294-308) Peptide - GWB-D727B1 from Genway Biotech
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Recombinant Human NPR1 - NPR1-28546TH from Creative Biomart
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Recombinant Human NPR1 - NPR1-150H from Creative Biomart
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Recombinant Natriuretic Peptide Receptor 1 (NPR1) - RPC665Hu01 from Uscn Life Science Inc.
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Recombinant Natriuretic Peptide Receptor 1 (NPR1) - RPC665Ra01 from Uscn Life Science Inc.
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Recombinant Natriuretic Peptide Receptor 1 (NPR1) - RPC665Hu01 from Cloud-clone
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Recombinant Human Atrial natriuretic peptide receptor 1(NPR1) - CSB-YP016023HU CSB-BP016023HU CSB-MP016023HU from Cusabio
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Recombinant Human Atrial natriuretic peptide receptor 1(NPR1) - CSB-EP016023HU from Cusabio
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Human NPR-A Peptide (OEMA00002) - OEMA00002 from Aviva Systems Biology
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ANPRA/Aequorin Expression vector - GWB-PS0F6A from Genway Biotech
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