NPR1

Gene Symbol	NPR1
Entrez Gene	4881
Alt Symbol	ANPRA, ANPa, GUC2A, GUCY2A, NPRA
Species	Human
Gene Type	protein-coding
Description	natriuretic peptide receptor 1
Other Description	ANP-A|ANPR-A|GC-A|NPR-A|atrial natriuretic peptide receptor 1|atrial natriuretic peptide receptor type A|atrionatriuretic peptide receptor A|guanylate cyclase A|natriuretic peptide A type receptor|natriuretic peptide receptor A|natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
Swissprots	Q5SR08 Q6P4Q3 P16066 B0ZBF0
Accessions	AAF01340 ACA05918 ACA05919 BAA31199 BAA77020 BAB03344 BAC53955 EAW53284 P16066 AK025024 AK298090 BAH12723 AK300446 BAG62168 BC063304 AAH63304 S72628 AAD14112 X15357 CAA33417 XM_005245218 XP_005245275 XM_006711342 XP_006711405 XM_006711343 XP_006711406 XM_011509585 XP_011507887 NM_000906 NP_000897
Function	Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand. {ECO:0000269|PubMed:1672777}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Top Pathways	Vascular smooth muscle contraction, Oxytocin signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Purine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

NPR-A CRISPR/Cas9 KO Plasmid (h) - sc-401737 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

NPR-A HDR Plasmid (h) - sc-401737-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NPR-A Double Nickase Plasmid (h) - sc-401737-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NPR-A Double Nickase Plasmid (h2) - sc-401737-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NPR-A CRISPR Activation Plasmid (h) - sc-401737-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

NPR-A CRISPR Activation Plasmid (h2) - sc-401737-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

NPR-A Lentiviral Activation Particles (h) - sc-401737-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NPR-A Lentiviral Activation Particles (h2) - sc-401737-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NPR-A siRNA (h) - sc-40125 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

NPR-A shRNA Plasmid (h) - sc-40125-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

NPR-A shRNA (h) Lentiviral Particles - sc-40125-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

NPRA/NPR1 RNAi - H00004881-R04 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU145391 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK1442 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1443 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1441 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN15467 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15467 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04943 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr04943

NPR1 siRNA (Human) - CRH3242 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human NPR1 (NM_000906.3) - SHH354392 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human NPR1(NM_000906.3) - SHR018798 from Creative biogene Category siRNA Species Reactivities Human

Human NPR1 siRNA - orb263744 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

NPR1 shRNA Plasmid (Human) - CHH3242 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

NPR1 miRNA 3'UTR clone - MiUTR1H-06880 from Creative biogene Species Reactivities Human

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