| Gene Symbol |
CDC23
|
| Entrez Gene |
8697
|
| Alt Symbol |
ANAPC8, APC8, CUT23
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cell division cycle 23
|
| Other Description |
anaphase promoting complex subunit 8|anaphase-promoting complex subunit 8|cell division cycle 23 homolog|cell division cycle protein 23 homolog|cyclosome subunit 8
|
| Swissprots |
B7WP05 Q9UJX2 Q53FN2 B4E3A2 Q9BS73 O75433 D3DQB7 A8K6E5
|
| Accessions |
AAS99353 EAW62154 EAW62155 EAW62156 Q9UJX2 AB011472 BAA75628 AF053977 AAC70920 AF191341 AAF05755 AK223250 BAD96970 AK291610 BAF84299 AK304635 BAG65414 BC005258 AAH05258 BC010944 AAH10944 BC017713 AAH17713 BT009810 AAP88812 DQ891686 ABM82612 DQ894870 ABM85796 NM_004661 NP_004652
|
| Function |
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. {ECO:0000269|PubMed:18485873}.
|
| Top Pathways |
Cell cycle, Ubiquitin mediated proteolysis, Progesterone-mediated oocyte maturation, Oocyte meiosis, HTLV-I infection
|
![Western Blot: Cdc23 Overexpression Lysate (Adult Normal) [NBL1-08993] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Cdc23.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5149_Cdc23%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-08993-img0002.jpg)