CDC23

Gene Symbol	CDC23
Entrez Gene	8697
Alt Symbol	ANAPC8, APC8, CUT23
Species	Human
Gene Type	protein-coding
Description	cell division cycle 23
Other Description	anaphase promoting complex subunit 8|anaphase-promoting complex subunit 8|cell division cycle 23 homolog|cell division cycle protein 23 homolog|cyclosome subunit 8
Swissprots	B7WP05 Q9UJX2 Q53FN2 B4E3A2 Q9BS73 O75433 D3DQB7 A8K6E5
Accessions	AAS99353 EAW62154 EAW62155 EAW62156 Q9UJX2 AB011472 BAA75628 AF053977 AAC70920 AF191341 AAF05755 AK223250 BAD96970 AK291610 BAF84299 AK304635 BAG65414 BC005258 AAH05258 BC010944 AAH10944 BC017713 AAH17713 BT009810 AAP88812 DQ891686 ABM82612 DQ894870 ABM85796 NM_004661 NP_004652
Function	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. {ECO:0000269|PubMed:18485873}.
Top Pathways	Cell cycle, Ubiquitin mediated proteolysis, Progesterone-mediated oocyte maturation, Oocyte meiosis, HTLV-I infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

APC8 CRISPR/Cas9 KO Plasmid (h) - sc-406761 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

APC8 HDR Plasmid (h) - sc-406761-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

APC8 Double Nickase Plasmid (h) - sc-406761-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

APC8 Double Nickase Plasmid (h2) - sc-406761-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

APC8 CRISPR Activation Plasmid (h) - sc-406761-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

APC8 CRISPR Activation Plasmid (h2) - sc-406761-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

APC8 Lentiviral Activation Particles (h) - sc-406761-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

APC8 Lentiviral Activation Particles (h2) - sc-406761-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

APC8 siRNA (h) - sc-37530 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

APC8 shRNA Plasmid (h) - sc-37530-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

APC8 shRNA (h) Lentiviral Particles - sc-37530-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU019471 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5774 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5774 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08913 from Sigma-Aldrich Category miRNA

CDC23 siRNA (Human) - CRH5723 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CDC23 - MBS8201861 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

APC8 CRISPR/Cas9 KO Plasmid (h2) - sc-406761-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

APC8 HDR Plasmid (h2) - sc-406761-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human CDC23 (NM_004661.3) - SHH259669 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human CDC23(NM_004661.3) - SHG160559 from Creative biogene Category siRNA Species Reactivities Human

Human CDC23 siRNA - orb266225 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CDC23 shRNA Plasmid (Human) - CHH5723 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

CDC23 miRNA 3'UTR clone - MiUTR1H-01930 from Creative biogene Species Reactivities Human

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