CDC23

Gene Symbol	CDC23
Entrez Gene	8697
Alt Symbol	ANAPC8, APC8, CUT23
Species	Human
Gene Type	protein-coding
Description	cell division cycle 23
Other Description	anaphase promoting complex subunit 8\|anaphase-promoting complex subunit 8\|cell division cycle 23 homolog\|cell division cycle protein 23 homolog\|cyclosome subunit 8
Swissprots	B7WP05 Q9UJX2 Q53FN2 B4E3A2 Q9BS73 O75433 D3DQB7 A8K6E5
Accessions	AAS99353 EAW62154 EAW62155 EAW62156 Q9UJX2 AB011472 BAA75628 AF053977 AAC70920 AF191341 AAF05755 AK223250 BAD96970 AK291610 BAF84299 AK304635 BAG65414 BC005258 AAH05258 BC010944 AAH10944 BC017713 AAH17713 BT009810 AAP88812 DQ891686 ABM82612 DQ894870 ABM85796 NM_004661 NP_004652
Function	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. {ECO:0000269\|PubMed:18485873}.
Top Pathways	Cell cycle, Ubiquitin mediated proteolysis, Progesterone-mediated oocyte maturation, Oocyte meiosis, HTLV-I infection

APC8 Antibody - 14185 from Cell Signaling Technology

Prices	$239.00
Sizes	100 µl (10 western blots)
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of extracts from various cell lines using APC8 Antibody.

APC8 (H-300) - sc-20988 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

APC8 (H-300): sc-20988. Western blot analysis of APC8 expression in HeLa whole cell lysate.

APC8 (D-7) - sc-514006 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

APC8 (D-7): sc-514006. Western blot analysis of APC8 expression in HeLa (A), SK-N-SH (B), K-562 (C) and HL-60 (D) whole cell lysates.

APC8 (S-17) - sc-249944 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-Cdc23 antibody - ab72206 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-Cdc23 antibody (ab72206) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µgLane 5 : Mouse NIH3T3 whole cell lysate at 50 µg

Anti-Cdc23 antibody - ab137461 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-Cdc23 antibody (ab137461) at 1/1000 dilutionLane 1 : H1299 whole cell lysateLane 2 : HeLa whole cell lysateLane 3 : HepG2 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-Cdc23 antibody - ab199407 from Abcam

Prices	$376.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-Cdc23 antibody (ab199407) at 1/200 dilutionLane 1 : RAW 264.7 cell lysateLane 2 : HepG2 cell lysateLysates/proteins at 40 µg per lane.

Anti-Cdc23 antibody - ab106496 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Lane 1 : Anti-Cdc23 antibody (ab106496) at 1 µg/mlLane 2 : Anti-Cdc23 antibody (ab106496) at 2 µg/mlLane 1 : K562 cell lysateLane 2 : K562 cell lysateLysates/proteins at 15 µg per lane.

Anti-Cdc23 antibody - ab66945 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-Cdc23 antibody (ab66945) at 1.25 µg/ml + Jurkat cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Cdc23 antibody - ab72213 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-Cdc23 antibody [EPR11827] - ab177148 from Abcam

Prices	$357.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR11827

All lanes : Anti-Cdc23 antibody [EPR11827] (ab177148) at 1/10000 dilutionLane 1 : HepG2 cell lysateLane 2 : HeLa cell lysateLane 3 : K562 cell lysateLane 4 : Jurkat cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-Cdc23 antibody [EPR11828] - ab182003 from Abcam

Prices	$357.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR11828

Immunofluorescent analysis of acetone-fixed HeLa cells labeling Cdc23 with ab182003 at 1/100 dilution, followed by Goat anti rabbit IgG (Alexa Fluor® 488) secondary at 1/200 dilution (Left panel). Counter stained with Dapi (Right panel).

Anti-CDC23 Antibody (Internal) IHC-plus™ - LS-B4647 from LifeSpan Bioscience

Prices	$395.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDC23 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4647 concentration 5 ug/ml.

Anti-CDC23 Antibody (aa125-175) - LS-C78930 from LifeSpan Bioscience

Prices	$545.00
Sizes	20 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDC23 Antibody (aa275-325) - LS-C288005 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CDC23 Antibody (aa125-175) - LS-C288003 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CDC23 Antibody (C-Terminus) - LS-C40404 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDC23 Antibody (aa101-150) - LS-C31946 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDC23 Antibody (aa491-592) - LS-C306859 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-CDC23 Antibody (aa220-269) - LS-C200133 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of the lysates from RAW264.7cells using APC8 antibody.

Anti-CDC23 Antibody (aa119-168) - LS-C170306 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDC23 Antibody (N-Terminus) - LS-C99345 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Formalin-fixed and paraffin-embedded human brain tissue reacted with CDC23 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Cdc23 Antibody - NBP1-55022 from Novus Biologicals

Prices	$299.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western Blot: Cdc23 Antibody [NBP1-55022] - Jurkat cell lysate, concentration 1.25ug/ml.

Cdc23 Antibody - NBP1-77156 from Novus Biologicals

Prices	$329.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western Blot: Cdc23 Antibody [NBP1-77156] - K562 cell lysate with Cdc23 antibody at (A) 1 and (B) 2 ug/mL.

Cdc23 Antibody - NB100-78338 from Novus Biologicals

Prices	$349.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: Cdc23 Antibody [NB100-78338] - la nuclear cell extract was resolved by electrophoresis, transferred to nitrocellulose and probed with anti-APC8 antibody. Proteins were visualized using a donkey anti-rabbit secondary conjugated to HRP and a chemiluminescence detection system.

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