BARD1

Gene Symbol BARD1
Entrez Gene 580
Alt Symbol -
Species Human
Gene Type protein-coding
Description BRCA1 associated RING domain 1
Other Description BRCA1-associated RING domain gene 1|BRCA1-associated RING domain protein 1
Swissprots F6MDH8 F6MDH7 Q99728 Q53SS5 O43574 F6MDH9
Accessions AAB99978 AAX93130 EAW70519 Q99728 AK223409 BAD97129 AK301843 BAG63286 AK310759 AK314260 BAG36925 AX794378 CAE48237 BC126426 AAI26427 BC126428 AAI26429 BU677525 BU753556 BX098964 DB088853 JF790280 AEF57471 JF790281 AEF57472 JF790282 AEF57473 JF790283 AEF57474 JF790284 AEF57475 JF790285 AEF57476 JF790286 AEF57477 JF790287 AEF57478 U76638 AAB38316 XM_011511567 XP_011509869 XM_011511568 XP_011509870 NM_000465 NP_000456 NM_001282543 NP_001269472 NM_001282545 NP_001269474 NM_001282548 NP_001269477 NM_001282549 NP_001269478 NR_104212 NR_104215 NR_104216
Function Probable E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage. {ECO:0000269|PubMed:12890688, ECO:0000269|PubMed:14976165, ECO:0000269|PubMed:20351172}.
Subcellular Location Nucleus. Note=During S phase of the cell cycle, colocalizes with BRCA1 into discrete subnuclear foci. Can translocate to the cytoplasm. Localizes at sites of DNA damage at double-strand breaks (DSBs); recruitment to DNA damage sites is mediated by the BRCA1-A complex.

Rabbit anti-BARD1 Antibody, Affinity Purified - PLA0074 from Sigma-Aldrich

Prices $323.50
Sizes 100 µl
<B>Immunofluorescence</B>: This antibody is qualified for the Proximity Ligation Assay (PLA). The above image shows representative results for PLA using three color fluorescence, including DAPI stained nuclei (blue), phalloidin stained cytoplasmic F-actin (green), and PLA positive signal (red).

BRCA1-associated RING domain protein 1 (BARD1), Human, ELISA Kit - E01B0747 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

BRCA1-associated RING domain protein 1 (BARD1), ELISA Kit - MBS7241477 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-associated RING domain protein 1 (BARD1), ELISA Kit - MBS7237135 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-associated RING domain protein 1 (BARD1), ELISA Kit - MBS7222349 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-associated RING domain protein 1 (BARD1), ELISA Kit - MBS7243894 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-associated RING domain protein 1 (BARD1), ELISA Kit - MBS7210873 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-associated RING domain protein 1 (BARD1), ELISA Kit - MBS7203505 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-associated RING domain protein 1 (BARD1), ELISA Kit - MBS7208117 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-associated RING domain protein 1 (BARD1), ELISA Kit - MBS7251395 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-associated RING domain protein 1 (BARD1), ELISA Kit - MBS7213769 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-associated RING domain protein 1 (BARD1), ELISA Kit - MBS7252206 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-associated RING domain protein 1 (BARD1), ELISA Kit - MBS7207926 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1 associated RING domain protein 1 (BARD1), ELISA Kit - MBS7236583 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human BARD1 ELISA Kit - E005273 from Biobool

Category ELISA Kit
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