SKA2

Gene Symbol SKA2
Entrez Gene 348235
Alt Symbol FAM33A
Species Human
Gene Type protein-coding
Description spindle and kinetochore associated complex subunit 2
Other Description family with sequence similarity 33, member A|spindle and KT (kinetochore) associated 2|spindle and kinetochore-associated protein 2
Swissprots B3KPL3 Q8WVK7 E9PCB8 A6NIL3
Accessions EAW94420 EAW94421 EAW94422 EAW94423 Q8WVK7 AK022820 AK056473 BAG51725 BC017873 AAH17873 BC106003 AAI06004 BQ019350 DA133216 DB158057 FJ648812 ACN41865 HQ447776 ADQ32261 XM_011524745 XP_011523047 NM_001100595 NP_001094065 NM_182620 NP_872426
Function Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it is required for SKA1 localization. {ECO:0000269|PubMed:17093495, ECO:0000269|PubMed:19289083}.
Subcellular Location Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Localizes to the outer kinetochore and spindle microtubules during mitosis in a NDC80 complex-dependent manner. Localizes to both the mitotic spindle and kinetochore-associated proteins.

Ska2 (S-13) - sc-136868 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
Ska2 (S-13): sc-136868. Western blot analysis of Ska2 expression in NIH/3T3 (A), 3T3-L1 (B), A549 (C) and Jurkat (D) whole cell lysates and MCF7 (E) and HeLa (F) nuclear extracts.

Ska2 (P-13) - sc-136867 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-SKA2 antibody - ab91551 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-SKA2 antibody (ab91551) at 0.5 µg/mlLane 2 : Anti-SKA2 antibody (ab91551) at 1 µg/mlLane 1 : 3T3 cell lysateLane 2 : 3T3 cell lysateLysates/proteins at 15 µg per lane.

Anti-SKA2 antibody - ab113067 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-SKA2 antibody (ab113067) at 1/100 dilution + T47D cell line lysate at 35 µg

Anti-SKA2 antibody - ab75345 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SKA2 antibody - N-terminal - ab189651 from Abcam

Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-SKA2 antibody - N-terminal (ab189651) at 0.5 µg/mlLane 2 : Anti-SKA2 antibody - N-terminal (ab189651) at 1 µg/mlLane 1 : 3T3 cell line lysateLane 2 : 3T3 cell line lysate

Anti-SKA2 Antibody (C-Terminus) - LS-C144909 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SKA2 Antibody (C-Terminus) - LS-C153561 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SKA2 Antibody (aa9-37, APC) - LS-C240823 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SKA2 Antibody (aa9-37, Biotin) - LS-C240824 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SKA2 Antibody (aa9-37, AP) - LS-C240825 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SKA2 Antibody (aa9-37, FITC) - LS-C240826 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SKA2 Antibody (aa9-37, PE) - LS-C240830 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SKA2 Antibody (aa16-45) - LS-C325130 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SKA2 Antibody (aa9-37, Azide-free, HRP) - LS-C248166 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SKA2 Antibody (aa9-37) - LS-C161109 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SKA2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human cervix tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-SKA2 Antibody (N-Terminus) IHC-plus™ - LS-B5038 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SKA2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5038 concentration 5 ug/ml.

SKA2 Antibody - NBP2-32443 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: SKA2 Antibody [NBP2-32443] - Staining of human heart muscle shows strong cytoplasmic positivity in myocytes.

SKA2 Antibody - NBP1-76312 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

SKA2 Polyclonal Antibody - bs-7847R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SKA2 antibody produced in rabbit - HPA059235 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SKA2: <B>Cat. No. HPA059235</B>: Immunohistochemical staining of Human heart muscle shows strong cytoplasmic positivity in myocytes.

Anti-SKA2 antibody produced in rabbit - SAB2900857 from Sigma-Aldrich

Prices $465.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SKA2 (N-Terminus), antibody produced in rabbit: <B>Cat. No. SAB2900857</B>: Anti-SKA2 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 μg/mL.

Anti-SKA2 antibody produced in rabbit - SAB3500102 from Sigma-Aldrich

Prices $316.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SKA2: <B>Cat. No. SAB3500102</B>: SKA2 in 3T3 cell lysate with SKA2 antibody at (A) 0.5 and (B) 1 μg/mL.

ANTI-SKA2 (N-TERM) antibody produced in rabbit - SAB1303230 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>SKA2 (N-term): <B>Cat. No. SAB1303230</B>: SKA2 in Human cervix tissue with SKA2 antibody (N-term) at 10 μg/mL.

SKA2-Antibody-N-term - AP12680a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
SKA2 Antibody (N-term) (Cat. #AP12680a) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the SKA2 antibody detected the SKA2 protein (arrow).
Search more