SKA2

Gene Symbol	SKA2
Entrez Gene	348235
Alt Symbol	FAM33A
Species	Human
Gene Type	protein-coding
Description	spindle and kinetochore associated complex subunit 2
Other Description	family with sequence similarity 33, member A|spindle and KT (kinetochore) associated 2|spindle and kinetochore-associated protein 2
Swissprots	B3KPL3 Q8WVK7 E9PCB8 A6NIL3
Accessions	EAW94420 EAW94421 EAW94422 EAW94423 Q8WVK7 AK022820 AK056473 BAG51725 BC017873 AAH17873 BC106003 AAI06004 BQ019350 DA133216 DB158057 FJ648812 ACN41865 HQ447776 ADQ32261 XM_011524745 XP_011523047 NM_001100595 NP_001094065 NM_182620 NP_872426
Function	Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it is required for SKA1 localization. {ECO:0000269|PubMed:17093495, ECO:0000269|PubMed:19289083}.
Subcellular Location	Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Localizes to the outer kinetochore and spindle microtubules during mitosis in a NDC80 complex-dependent manner. Localizes to both the mitotic spindle and kinetochore-associated proteins.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SKA2 full length protein - ab199577 from Abcam Category Protein Source E. coli Species Human

SKA2 Antibody Blocking Peptide - LS-E1863 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SKA2 Antibody Blocking Peptide - LS-E30779 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

SKA2 Blocking Peptide - NBP1-76312PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

SKA2-Antibody-N-term-Blocking-peptide - BP12680a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SKA2 Peptide - GTX85247-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

SKA2 Control Peptide - AP30788CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

SKA2 Peptide - 5403P from ProSci Category Peptide Species Human

Recombinant Human Spindle and kinetochore-associated protein 2(SKA2) - CSB-YP823890HU CSB-EP823890HU CSB-BP823890HU CSB-MP823890HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SKA2 Protein - NBP2-32443PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

SKA2 Peptide, Human - M34GP14283H from Creative Peptides Category Peptide Source Synthetic. Species Human

Spindle and kinetochore-associated protein 2 (SKA2), Recombinant Protein - MBS1346501 from MyBioSource Category Protein Prices $855.00, $855.00, $1,080.00, $1,080.00, $1,240.00, $1,240.00, $1,695.00, $1,695.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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