Gene Symbol | CHST13 |
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Entrez Gene | 166012 |
Alt Symbol | C4ST3 |
Species | Human |
Gene Type | protein-coding |
Description | carbohydrate (chondroitin 4) sulfotransferase 13 |
Other Description | C4ST-3|carbohydrate sulfotransferase 13|chondroitin 4-O-sulfotransferase 3|chondroitin 4-sulfotransferase 3 |
Swissprots | Q8NET6 Q3SYA3 Q3SYA5 |
Accessions | EAW79359 Q8NET6 AY120869 AAM55481 BC039390 AAH39390 BC045257 BC047236 AAH47236 BC103895 AAI03896 BC103896 AAI03897 BC103897 AAI03898 DR006930 NM_152889 NP_690849 |
Function | Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Transfers sulfate to the C4 hydroxyl of beta1,4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. No activity toward dermatan. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Tissue Specificity | Highly expressed in adult liver. Expressed at lower level in kidney, lymph nodes and fetal kidney. {ECO:0000269|PubMed:12080076}. |
Top Pathways | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate |
C4ST-3 (V-20) - sc-68016 from Santa Cruz Biotechnology
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Anti-CHST13 antibody - ab110762 from Abcam
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Anti-CHST13 antibody - ab75795 from Abcam
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Anti-CHST13 antibody - ab73062 from Abcam
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Anti-CHST13 antibody [EPR9344] - ab155957 from Abcam
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Anti-CHST13 Antibody (aa211-260) - LS-C291299 from LifeSpan Bioscience
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Anti-CHST13 Antibody (aa38-87) - LS-C82557 from LifeSpan Bioscience
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Anti-CHST13 Antibody (aa254-303) - LS-C82558 from LifeSpan Bioscience
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CHST13 Antibody - NBP1-62293 from Novus Biologicals
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CHST13 Antibody - NBP1-62294 from Novus Biologicals
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CHST13 Antibody - H00166012-B01 from Novus Biologicals
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Anti-CHST13 (AB2) antibody produced in rabbit - AV49073 from Sigma-Aldrich
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Anti-CHST13 antibody produced in rabbit - SAB4300763 from Sigma-Aldrich
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Anti-CHST13 (AB1) antibody produced in rabbit - AV49072 from Sigma-Aldrich
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CHST13 antibody - N-terminal region (ARP49072_P050) - ARP49072_P050 from Aviva Systems Biology
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CHST13 antibody - C-terminal region (ARP49073_P050) - ARP49073_P050 from Aviva Systems Biology
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CHST13 antibody - GTX87515 from GeneTex
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CHST13 Antibody (OAAF03424) - OAAF03424 from Aviva Systems Biology
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CHST13 antibody - 70R-7171 from Fitzgerald
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CHST13 antibody - 70R-21483 from Fitzgerald
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CHST13 antibody - orb194435 from Biorbyt
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CHST13 antibody - 70R-7172 from Fitzgerald
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CHST13 antibody - 70R-35537 from Fitzgerald
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CarbohydRate (Chondroitin 4) Sulfotransferase 13 Antibody - abx111365 from Abbexa
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CHST13 Antibody - abx014304 from Abbexa
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