Gene Symbol | BATF2 |
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Entrez Gene | 116071 |
Alt Symbol | SARI |
Species | Human |
Gene Type | protein-coding |
Description | basic leucine zipper transcription factor, ATF-like 2 |
Other Description | B-ATF-2|basic leucine zipper transcriptional factor ATF-like 2|suppressor of AP-1 regulated by IFN |
Swissprots | D9IC56 Q8N1L9 Q96EH4 Q8NAF4 Q8NAL8 |
Accessions | EAW74330 EAW74331 Q8N1L9 AK092453 BAC03894 AK096702 BAC04846 AK300917 BAG62549 BC011931 BC012330 AAH12330 BP206576 HM134154 ADJ55304 XM_011544750 XP_011543052 NM_001300807 NP_001287736 NM_001300808 NP_001287737 NM_138456 NP_612465 |
Function | AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes (By similarity). Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter. {ECO:0000250, ECO:0000269|PubMed:20531301}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978}. |
BATF2 (E-18) - sc-241888 from Santa Cruz Biotechnology
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BATF2 (P-16) - sc-241887 from Santa Cruz Biotechnology
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BATF2 (L-24) - sc-130972 from Santa Cruz Biotechnology
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Anti-MGC20410 antibody - ab192418 from Abcam
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Anti-MGC20410 antibody - ab98350 from Abcam
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Anti-MGC20410 antibody [EPR10667] - ab157466 from Abcam
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Anti-BATF2 / SARI Antibody (aa16-43, AP) - LS-C233067 from LifeSpan Bioscience
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Anti-BATF2 / SARI Antibody (aa16-43, APC) - LS-C233069 from LifeSpan Bioscience
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Anti-BATF2 / SARI Antibody (aa16-43, Biotin) - LS-C233070 from LifeSpan Bioscience
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Anti-BATF2 / SARI Antibody (aa16-43, FITC) - LS-C233071 from LifeSpan Bioscience
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Anti-BATF2 / SARI Antibody (aa16-43, PE) - LS-C233072 from LifeSpan Bioscience
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Anti-BATF2 / SARI Antibody (aa116-165) - LS-C82521 from LifeSpan Bioscience
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Anti-BATF2 / SARI Antibody (aa16-43, Azide-free, HRP) - LS-C249504 from LifeSpan Bioscience
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Anti-BATF2 / SARI Antibody - LS-C306501 from LifeSpan Bioscience
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Anti-BATF2 / SARI Antibody (N-Terminus) - LS-C107895 from LifeSpan Bioscience
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Anti-BATF2 / SARI Antibody - LS-C306502 from LifeSpan Bioscience
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Anti-BATF2 / SARI Antibody (aa15-43) - LS-C319780 from LifeSpan Bioscience
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Anti-BATF2 / SARI Antibody (aa16-43) - LS-C159162 from LifeSpan Bioscience
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Anti-BATF2 / SARI Antibody - LS-C340950 from LifeSpan Bioscience
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Anti-BATF2 / SARI Antibody (N-Terminus) - LS-C345455 from LifeSpan Bioscience
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MGC20410 Antibody - NBP1-79268 from Novus Biologicals
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MGC20410 Antibody - NBP1-79267 from Novus Biologicals
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MGC20410 Antibody - NBP2-38963 from Novus Biologicals
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MGC20410 Antibody - H00116071-B02P from Novus Biologicals
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MGC20410 Antibody (1B11) - H00116071-M01 from Novus Biologicals
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